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2 September, Friday
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Small Hall BGRS\SB
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9:00–16.30
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Section “Genomics, Transcriptomics and Bioinformatics” (House of Scientists SB RAS, Small hall)
Chairpersons: Ivo Grosse, Halle-Wittenberg University, Halle, Germany; Vsevolod Makeev, VIGG RAS, MIPT, Moscow, Russia
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9:00–9.15
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Sequencing from Roche: what the future will bring for you?
Irina Karpova
LCC “Roche Diagnostics Rus”, Moscow, Russia
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9.15–9.30
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Whole genome of the wooly mammoth: evolution through millenia
Artem Nedoluzhko1,*, A.S. Sokolov2, F.S. Sharko2, E.S. Boulygina1, S.V. Tsygankova1, A.N. Tikhonov3, K.G. Skryabin1,2,4, E.B. Prokhortchouk2,4
1National Research Center “Kurchatov Institute”, Moscow, Russia; 2Institute of Bioengineering, Research Center RAS, Moscow, Russia; 3Zoological Institute, Russian Academy of Sciences, Saint Petersburg, Russia; 4Lomonosov Moscow State University, Moscow, Russia
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9.30–9.45
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Opisthorchiidae triad: comparative genomics of the carcinogenic liver flukes using a draft genome of Opisthorchis felineus
N. Ershov1*, G. Fan2,3, E. Prokhortchouk4, V. Solovyev5, Dmitry Afonnikov1,6, H. Yang2, V. Mordvinov1, X. Liu2, K. Skryabin4,7 and The Opisthorchis Genome Consortium
1ICG SB RAS, Novosibirsk, Russia; 2BGI-Shenzhen, Shenzhen, China; 3State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China; 4Russian Federal Research Center for Biotechnology, Moscow, Russia; 5Softberry Inc., Mount Kisco, NY, US; 6NSU, Novosibirsk, Russia; 7National Research Centre, Kurchatov Institute, Moscow, Russia
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9.45–10:00
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In silico mouse chromocenters content
Dmitrii Ostromyshenskii, A.S. Komissarov, I.S. Kuznetsova, O.I. Podgornaya
Institute of Cytology RAS, St. Petersburg, Russia
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10:00–10:15
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Transcriptome wide prediction of lncRNA-RNA interactions by a thermodynamics algorithm
Ivan Antonov, M.A. Zamkova, A.V. Marakhonov, M.Y. Skoblov, Y.A. Medvedeva
Research Center of Biotechnology RAS, Moscow, Russia
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10:15–10:30
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Energy metabolic dysfunction in tumor cells, molecular mechanisms and clinical significance
Anna Kudryavtseva1,2, A.A. Dmitriev1, O.L. Kardymon1, A.S. Zasedatelev1, G.S. Krasnov1, A.V. Snezhkina1
1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
2Herzen Moscow Cancer Research Institute, Ministry of Health of the Russian Federation, Moscow, Russia.
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10:30–11:00
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GeneQuery: globally connected networks of GEO transcriptional profiles show hypothesis generation potential and reveal that tocopherols rescue TREM2-associated microglial dysfunction
Aleksandr Predeus1,2*, T. Ulland1, Y. Wang1, V. Lampropoulou1, W. Song1, I. Arbuzov3, F. Towfic4, S. Gilfilan1, E. Loginicheva1, B.T. Edelson1, B. Zeskind4, M. Colonna1, M.N. Artyomov1
1Washington University School of Medicine, St. Louis, MO, USA; 2Bioinformatics institute, Saint Petersburg, Russia; 3ITMO University, Saint Petersburg, Russia.
4Immuneering Corporation, Cambridge, MA, USA
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11.00–11.20
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Coffee break
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11.20–11.50
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miRNA binding sites in the mRNA of human titin gene
Ilya Pinsky1, A.T. Ivashchenko1, S.B. Labeit2
1Al-Farabi Kazakh National University, Almaty, Kazakhstan
2Institute of Integrative Pathophysiplogy, Mannheim, Germany
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11.50–12.05
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Genome-wide transcriptomics as a platform for understanding the unusual resistance to muscle atrophy in hibernating dormice
Guzel Gazizova1*, O.V. Tyapkina2, O.S. Kozlova1, M.D. Logacheva1,3, L.F. Nurullin2, I.M. Vikhlyantsev4, O.A. Gusev1,5
1Kazan Federal University, Kazan, Russia;
2Kazan Institute of Biochemistry and Biophysics KSC RAS, Kazan, Russia;
3Lomonosov Moscow State University, Moscow, Russia;
4Institute of Theoretical and Experimental Biophysics RAS, Puschino, Russia;
5RIKEN, Yokohama, Japan
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12.05–12.35
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The first edition of mutagenesis by CRISPR/Cas in the extreme desiccation tolerant cultured cell.
Takahiro Kikawada1,2, Y. Miyata1,3, Y. Sogame1,4, T. Furusawa1, S. Kikuta5, R. Cornette1, O. Gusev6,7
1Institute of Agrobiological Sciences, NARO, Japan
2Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Japan
3Center for Biological Resources and Informatics, Tokyo Institute of Technology, 4. JSPS Research Fellow, 5. Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan, 6. Institute of Fundamental Medicine and Biology, Kazan Federal University , Russia, 7. Preventive Medicine & Diagnosis Innovation Program (PMI), RIKEN, Japan
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12.35 -14:00
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Lunch
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14:00-16:00
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Expert-analytical evaluation of promising research directions in bioinformatics and systems biology
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16:00-16:30
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Closing
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