10th anniversary International Multiconference «Bioinformatics of Genome Regulation and Structure\ Systems Biology»

Perspectives for the prevention of accelerated aging

Vladimir Anisimov

Department of Carcinogenesis and Oncogerontology, N.N. Petrov Research Institute of Oncology, St-Petersburg, Russia

16:30-17:00

Structural bioinformatics of Fpg glycosylase: search for substrate specificity in the sequence space Anna Yudkina ICBFM SB RAS, Novosibirsk, Russia

16:15–16:30

How new science emerges: a case study of microrna research Igor Titov^1,2, A.B. Firsov^2, S.I. Demurin^2, M.V. Pankova^2 ^1Institute of Cytology and Genetics SBRAS, Novosibirsk, Russia ^2NSU, Novosibirsk, Russia

17.00–17.25

Molecular modeling of influenza virus H1N1 hemagglutinin inhibition by camphor imines Dmitry Baev, A.S. Sokolova, O.I. Yarovaya, T.G. Tolstikova, V.V. Zarubaev N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Novosibirsk, Russia

17.00–17.25

Systems biology, control theory and origin of aging Alexander Khalyavkin, V.N. Krut’ko Institute of Biochemical Physics of RAS and FRC CSC RAS, Moscow, Russia

17:00-17:30

DNA repair and death signalling targeted by alkylating anticancer drugs Bernd Kaina Department of Toxicology, University Medical Center, Mainz, Germany

16:30–18:00

Poster Session

17.25–17.50

Small molecule agonists of relaxin receptor Alexander Agoulnik^1, I.U. Agoulnik^1, X. Hu^2, C. Myhr ^1, Z. Huang^1, B.A. Ho^1, E. Barnaeva^2, J. Xiao^2, M. Ferrer^2, N.T. Southall^2, J.J. Marugan^2 ^1Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA; ^2NIH Chemical Genomics Center, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA

17.25–17.50

The role of the mechanisms of resistance to ionizing radiation in Drosophila melanogaster aging and longevity Mikhail Shaposhnikov^1,2, E.N. Proshkina^1,2, L.A. Shilova^1, D.O. Peregudova^1, S.O. Zhikrivetskaya^3, A.A. Moskalev^1-4 ^1Institute of Biology of Komi Science Center UB RAS; ^2Syktyvkar State University, Syktyvkar; ^3Engelhardt Institute of Molecular Biology RAS; ^4Moscow Institute of Physics and Technology, Dolgoprudny, Russia

17:30-18:00

Modulation of cognitive function by oxidative DNA base lesion repair K. Scheffler^2, V. Rolseth^1, M.D. Bjørge^1, G. Hildrestrand^1, W. Wang^2, R. Suganthan^2, A. Kusnierczyk^2, Ch. Neurauter^1, H. Korvald^1, C. Vågbø^2, L. Luna^1, G. Slupphaug^2, L. Eide^2, Magnar Bjørås^1,2 ^1Department of Microbiology, University of Oslo, Oslo, Norway; ^2Department of Cancer Research and Molecular Medicine, Norwegian University of Technology and Natural Sciences, Trondheim, Norway.

17.50–18.10

The impact of human genetic variability on ligand-protein interactions and individual drug response Peter Vlasov, O. Pich i Rosello, A.V. Vlasova, F.A. Kondrashov Centre for Genomic Regulation; Universitat Pompeu Fabra; Institució Catalana de Recerca i Estudis Avançats, Barcelona, Spain

18:00-18:20

DNA damage initiating demethylation: a repair-epigenetic connection Inga Grin^1,2, A.A. Ishchenko^3 ^1ICBFM SB RAS, Novosibirsk, Russia ^2NSU, Novosibirsk, Russia ^3CNRS UMR 8200, Gustave Roussy Cancer Campus, Villejuif, France

18:20-18:30

Systemic response to genetic and chemical modulation of DDR regulating wild type p53 induced phosphatase in skin, intestine and hematopoietic system A.R. Goloudina^2, B.B. Grigorash^1, E.Y. Kochetkova^1, E. Appella^3, V.A. Pospelov^1, Oleg Demidov^1,2 ^1Institute of Cytology RAS, St. Petersburg, Russia; ^2University of Burgundy, France; ^3NCI, NIH, Bethesda, USA

18:30-18:45

The functional interactions of pleiotropic protein yb-1 with key base excision repair factorsa Elizaveta Alemasova^1, N.A. Moor^1, K.N. Naumenko^1,2, P.E. Pestryakov^1, O.I. Lavrik^1,2 ^1ICBFM SB RAS, Russia ^2NSU, Novosibirsk, Russia

19:30 – 22:00

The program dedicated to the 10th Anniversary of the BGRS Conference (including banquet) Technopark of Novosibirsk Akademgorodok, Novosibirsk, Nikolaeva street, 11, floor 13