MATERIALS AND METHODS
SETTING AND PATIENTS
Over a 36 month period (January 2012 to December 2014),
this retrospective study was performed in ICU departments
HEALTHCARE-ASSOCIATED INFECTIONS IN INTENSIVE CARE
UNITS
Aidyn Salmanov, Viktor Litus, Sergiy Vdovychenko, Oleksandr Litus, Lena Davtian, Sergiy Ubogov, Yuriy Bisyuk
,
Anna Drozdova, Iryna Vlasenko
THE SHUPYK NATIONAL MEDICAL ACADEMY OF POSTGRADUATE EDUCATION, KYIV, UKRAINE
ABSTRACT
Introduction:
Healthcare-associated infections (HAIs) remain a major public health problem and patient safety threat worldwide. Scant information is available on the occurrence
HAI and antimicrobial susceptibility of responsible pathogens in Ukrainian intencive care units (ICUs).
The aim:
To evaluate the prevalence of HAIs and antimicrobial resistance of the responsible pathogens.
Materials and methods:
The study included 642 patients and 262 samples isolated from patients with microbiologically proven HAI. The identification and antimicrobial
susceptibility of the cultures were determined, using automated microbiology analyzer. Some antimicrobial susceptibility test used Kirby — Bauer antibiotic testing. Interpretative
criteria were those suggested by the Clinical and Laboratory Standards Institute.
Results:
Among 642 patients, 148 HAIs were observed (23.1%). Death during hospitalization was reported in 20.1% HAI cases. Pneumonia (47.3%), blood stream infection
(21.6%), and urinary tract infection (14.9) together accounted for 83.8% of all HAIs reported. Most cases of these infections were device-associated. Considering all HAI types
together,
Klebsiella pneumoniae
were most commonly reported, accounting for 21.8% of all organisms, followed by
Acinetobacter
baumanni
(14.3%),
Pseudomonas aeruginosa
(12.4%) and
Escherichia coli
(9.4%). 59.8% and 6.6% of
Staphylococcus aureus
were oxacillin and teicoplanin resistant, respectively. Third-generation cephalosporins resistance
was found in 53.8% of
K.pneumoniae
and 32.1% of
E.coli
isolates; and carbapenem resistance in 78.6% of
A. baumanni
and 29.3% of
K. pneumoniae
isolates.
Conclusions:
Infection control priorities in intensive care units should include preventing nosocomial pneumonia, blood stream infection, urinary tract infection and of device-
associated infections.
Dostları ilə paylaş: |
