Biotech Networks
k
BioTOP Berlin-Brandenburg
k
BioHyTec Network for Biohybrid Technologies
k
BioResponse
k
Center for Molecular Diagnostics and Bioanalytics (ZMDB)
k
DiagnostikNet-BB
k
GABI – Genome Analysis in the Plant Biological System
k
NetDDD Network for Drug Discovery & Development Berlin-Brandenburg
k
Network Glycobiotechology Berlin-Brandenburg
k
Nutrigenomics Network Berlin-Brandenburg
k
Regenerative Medicines Initiative Berlin-Brandenburg
k
RiNA Network for RNA Technologies
Scientific Institutions
k
Berlin-Brandenburg Center for Regenerative Therapies
k
Berlin
Institute of Technology
k
Brandenburg University of Technology
k
Charité – Universitätsmedizin Berlin
k
Fraunhofer Institute for Applied Polymer Research
k
Fraunhofer Institute for Biomedical Engineering (IBMT)
k
Freie Universität Berlin
k
German Heart Instiute Berlin
k
German Institute of Human Nutrition (DIfE)
k
German Rheumatism Research Center (DRFZ)
k
Humboldt-Universität zu Berlin
k
Institute of Polymer Research of the GKSS Research Centre
k
Lausitz University of Applied Sciences
k
Leibniz-Institute for Agricultural Engineering Potsdam-Bornim (ATB)
k
Leibniz-Institut für Molekulare Pharmakologie (FMP)
k
Leibniz-Zentrum für Agrarlandschaftsforschung (ZALF) e. V.
k
Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch
k
Max-Planck-Institute for Colloids and Interfaces
k
Max Planck Institute for Infection Biology
k
Max Planck Institute for Molecular Genetics
k
Max Planck Institute
of Molecular Plant Physiology
k
Robert Koch Institute
k
University of Applied Sciences Berlin
k
University of Applied Sciences Wildau
k
University of Potsdam
36
BioTOPics 44 | May 2012
BioTOP-Report
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Bioparks
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Networks
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Scientific Institutions
P
Companies
caprotec bioanalytics GmbH
caprotec bioanalytics GmbH has developed
a ground-breaking, proprietary technology
to reduce the complexity of protein mixtures
in a targeted and directed manner.
Founded in 2006 by scientist and entrepre-
neur Prof. Dr. Hubert Köster, founder of
Sequenom Inc. and Biosyntech, caprotec
raised since 2007 approx. 11 million Euro.
Caprotec is operational in Berlin Adlershof
since September of 2008 and currently has
26 employees.
caprotec’s Capture Compound Mass Spec-
trometry (CCMS) Technology is based on
multifunctional small molecules that are
used to target, capture, and isolate proteins
based on their function. The company is
commercializing the CCMS technology as
kits for research applications and in the form
of interactive research collaborations with
the pharmaceutical, biotech and agrobio-
chemical industry. In collaborations for drug
development caprotec is using small mole-
cule drugs or drug candidates to establish a
profile of proteins that interact specifically
with the small molecule drug in a mixture of
human proteins. The profile can be used to
elucidate the mode of action of drugs and
drug candidates and also to discover off-tar-
get proteins that potentially could cause
adverse side effects in humans, e.g. liver
toxicity.
Address
caprotec bioanalytics GmbH
Volmerstraße 5 · 12489 Berlin · Germany
Contact
caprotec bioanalytics GmbH
Phone +49 30 63 92 3990
info@caprotec.com · www.caprotec.com
CCMS profiles small molecule interactions with the proteome
Sorting function
(isolates drug/molecule‘s specific
binding partners)
Photoreactivity function
(captures protein binding partners)
Selectivity function
(drug/molecule of choice)
k
Target ID
k
Toxicity ID
k
Pathway analysis
38
BioTOPics 44 | May 2012
BioTOP-Report
Biochrom AG
Biochrom AG is a company dedicated to
be a primary supplier of cell culture
media and quality animal sera.
The company manufactures and distributes
the full range of products related to mam-
malian cell culturing technique: standard
cell culture media, complete media tailored
for particular cell types and cell lines, cus-
tom formulations, and animal sera, such as
Fetal Bovine Serum (FBS). All sera are pre-
screened prior to acceptance; only those lots
that meet strict quality control requirements
are accepted for further processing and sub-
sequent sale to customers. Serum products
are tested for sterility, adventi
tious viral
agents, physico-chemical parameters, and
biological performance. The manufacturing
processes are de
signed for the specific
needs of customers engaged in biotechno-
logical research, development, and biophar-
maceutical production. Biochrom AG spe-
cializes in meeting customers‘ specifications
and regulatory concerns, to facilitate the
manufacture of custom media consistent
with Good Manufacturing Practice (GMP).
The media are produced in a strictly con-
trolled environment; chemicals used con-
form, where applicable, to grade standards
of European Pharmacopoeia and US Pharma-
copoeia. Biochrom AG produces lot sizes of
sterile industrial buffers up to 4,000 litres,
sterile media up to 2,000 litres, powder
media up to 20,000 litres and customized
sizes in smallest quantities.
Biochrom AG and TPP Techno Plastic
Products AG (Switzerland) are exclusive
partners for the sale of TPP products for
cell culture and general laboratory equip-
ment in Germany.
Address
Biochrom AG
Leonorenstraße 2-6
12247 Berlin · Germany
Phone +49 30 779 90 60
Fax
+49 30 771 00 12
info@biochrom.de
www.biochrom.de