1
1
1
2
2
7 Virus: * Morphological characteristics
* Cultivation of viruses, Reproduction
* Oncogenic and HIV viruses
2
8 Yeasts / Molds: * Morphology, habitat, nutrition
* Reproduction in yeast
* Molds of Clinical significance
1
9 Algae * Morphology habitat
* Economic significance of algae
1
10 Protozoa * Morphology
* Clinical significance of protozoa
1
11 Rickettsiae * Morphology (diseases caused malaria, amoebic dysentery)
* Diseases caused by rickettsiae
1
12 Microbial Mutation
* Types of mutation
* Mutagenic agents
* Mechanism of mutation
2
13 Diseases caused by the following microorganisms and their detection
1) Mycobacterium
2) Salmonella
3) E. coli
4) Clostridium
5) Staphylococcus
2
14 Sterilization - Different methods of sterilization
- Aseptic techniques
5
15 Disinfection and disinfectants 1
16 Tutorials 3
13
Books Recommended
Sr. No. Title Of The Book Author/Editor Edition/Year Publisher
1 Microbiology Concepts
And Applications
M. J. Pelczar Jr., E.
C. S. Chan And N.
R. Krieg
5th ,1996 McGraw Hill, Inc., USA
2 Fundamentals Of
Microbiology
M.Frobisher, R. D.
Hinsdill, K. T.
Crabtree And C. R.
Goodheart
9th ,1968 Saunders College
Publishing, Philadelphia
3 Pharmaceutical
Microbiology
W. B.Hugo And A.
D. Russel
6th , 2003 Blackwell Science Ltd. Uk,
4 Text Book Of
Microbiology
R. Ananthanarayan
And C.K. J.
Paniker
7th , 2005 Orient Longman Pvt. Ltd.
Hyderabad,
14
Laboratory
Title of the Course Organic Chemistry Laboratory-I
Marks 50
Number of Hours per Week 4
Total Hours 60
Class F.Y. B.Pharm
Semester I
Sr.No Experiment Hrs.
Organic Spotting: Qualitative analysis of organic compounds -aspects to be covered are:
1 Solubility, characterization and preliminary tests, 16
2 Elements detection, 8
3 Functional group characterization, 20
4 Derivative preparation. 16
Books Recommended Will be recommended by the teacher
Title of the Course Microbiology Laboratory
Marks 50
Number of Hours per Week 4
Total Hours 60
Class F.Y B.Pharm.
Semester I
Sr.No. Experiment Hrs.
1 Study of microscope 4
2 Study of common laboratory equipments: autoclave, incubator, hot air oven etc. 4
3 Gram Staining 4
4 Monochrome staining 4
5 Negative staining 4
6 Cell Wall Staining 4
7 Spore Staining 4
8 Capsule Staining 4
9 Motility by hanging drop technique 4
10 Preparation and sterilization of nutrient broth, agar, slants, stab etc. 4
11 Inoculation techniques: Colony characteristics, Growth patterns in broth, slant- pour
& streak plate technique.
4
12 Total count by Haemocytometer Growth by optical density+ 4
13 Total plate count, TDP, TDT 4
14 Study of yeast- Aspergillus, Penicillium with respect to morphology 4
15 Studies as prepared sides – malarial parasite in blood smear, intestinal amoeba in
stools.
4
Books Recommended: Will be recommended by teacher
15
Title of the Course Anatomy, Physiology & Pathophysiology Laboratory
Marks 50
Number of Hours per Week 4
Total Hours 60
Class F.Y B. Pharm
Semester I
Sr.
No.
Experiment Hrs.
1 HEMATOLOGY
1. Red Blood Cell (RBC) Count,
2. Total leukocyte Count
3. Differential Leukocyte (WBC) count
4. Hemoglobin content of blood
5. Bleeding/Clotting time
6. Blood groups
7. Erythrocyte Sedimentation rate (ESR)/Hematocrit (Demonstration)
8. Measurement of blood pressure
4
4
4
4
4
4
2
2
2 Study of human skeleton 4
3 Microscopic study of permanent slides
Tissues:
- Columnar, Cuboidal, Squamous, Ciliated Epithelium
- Cardiac/Skeletal/Smooth muscle
- Ovary, testis, Liver, Pancreas, Thyroid, Tongue, Stomach, Intestine,
Kidney, Lung, Spinal Cord, Cerebrum, Artery, Vein
12
4 Discussion on some common investigational procedures used in diagnosis of diseases
with the help of charts/ slides
Name and Importance of following Tests:
1) Electroencephalogram(EEG) in diagnosis of epilepsy
2) Electrocardiagram (ECG) in diagnosis of cardiac arrhythmia
3) Liver Function tests-
- Serum Bilirubin, Serum glutamate oxaloacetate transaminase (SGOT), Serum
glutamate pyruvate transaminase (SGPT)
- Urine Bilirubin, Urine Urobilinogen
Kidney Function Tests
Serum Creatinine, Serum Urea, Uric acid, Serum Urea Nitrogen BUN)
Blood Glucose
Serum Cholesterol/Triglycerides
Serum Alkaline phosphate (ALT)
Serum acid phosphatase (APT)
Serum Lipase, Serum Amylase, Serum Calcium
12
16
Serum Lactate dehydrogenase ( LDH)
Thyroid Function tests- T3, T4
Diagnostic tests for infectious diseases like
- Malaria, Tuberculosis, Dengue, Leptospirosis
Books Recommended
Sr.No. Title Of The Book Author/Editor Edition/Year Publisher
1 Textbook Of Medical
Laboratory Technology
Praful B. Godkar 2nd 2006 Bhalani Publishing House,
Mumbai
2 A Textbook Of Practical
Physiology
V.G. Ranade,
P.N. Joshi And
Shalini Pradhan
3rd 1982 P.V.G. Prakashan, Pune-30
First Year B.Pharm.
SEMESTER-II
Title of the Course Organic Chemistry-II
Marks 50
Number of Hours per Week 2
Total Hours 30
Class F.Y. B.Pharm
Semester II
Sr.No. Topic Hrs.
Heterocyclic Compounds
Discussion of the following classes of compounds including (aromatic to saturated)
with regard to IUPAC nomenclature, structure, pKa, etc. sources, methods of
preparation, structure and physical properties(Structure property relationships), and
reactivity:
1 Three and four member ring compounds containing N, O 3
2 Five membered rings containing N,O,S 10
3 Six membered rings containing N,O,S 5
4 Seven membered rings containing N, O, S 2
Stereochemistry
5 Enantiomers, diastereomers, configuration notations, Properties to
characterize the enantiomers
4
6 Conformations and conformational analysis: n-butane, alicyclic, and
saturated heterocyclic systems and implication on reactivity
6
17
Books Recommended
Sr.No Title of the Book Author/Editor Edition/Year Publisher
1 Adv.Org. Chemistry Carey 4th, 2001 Plenum Press NY
2 Organic Chemistry Morrison, R. T 6th, 1992 Pearson Education
3 Organic Chemistry Solomons, T. W.G 8th , 2004 John Wiley & Sons, Inc
4 Organic Chemistry Loudon, G. Marc 4th ,2002 Oxford University Press
5 Introduction to Organic
Chemistry
Andrew 4th,1992 Macmillan Publishing
6 Organic Chemistry
Structure and Reactivity
Seyhan Ege 5th , 2004 Houghton Millin
Company, NY
7 Chemistry of
Heterocyclic Compounds
Weissberger, N. 1972 John Wiley & Sons, Inc
Title of the Course Mathematics-II
Marks 50
Number of Hours per Week 2
Total Hours 30
Class F.Y. B. Pharm.
Semester II
Prerequisites: Notions of sets and functions, basic probability theory, Measures of
central tendency: Arithmetic mean, median and mode; Measures of dispersion: Range,
quartile deviation, mean deviation and standard deviation; Coefficient of variation,
moments, skewness and kurtosis.
Sr. No. Topic Hrs.
1 Probability Distributions: Discrete and continuous random variables,
Probability distribution functions, expectation of random variables, mean,
variance and moments of random variables, moment generating function,
Binomial, Poisson and Geometric distributions, Normal, uniform and Gammabeta
distribution functions, chi-square distribution, F-distribution, Joint
distributions, notion of covariance.
9
2 Sampling distribution, Point and interval estimations of mean, variance and
proportion of single and multiple samples.
4
3 Hypothesis testing: Inferences concerning mean, variance and proportions, Chisquare
test, goodness of fit.
4
4 Regression and Correlation: Linear non linear regression, Correlation,
multilinear regression.
5
5 Design of experiments: One-way and two way ANOVA tests. 5
6 Non Parametric tests: Sign test, Rank sum test, Wilcoxon and Kruskal-Vallis test. 3
18
Books Recommended
Sr.No. Title of The Book Author/Editor Edition/Year Publisher
1. A First Course In
Probability
Sheldon Ross 6th , 2002 Prentice Hall
2. Miller & Freund's
Probability And Statistics
For Engineers
Richard Johnson,
Irwin Miller,
John Freund
7th , 2005 Pearson Education
3. Pharmaceutical Statistics:
Practical And Clinical
Applications
Sanford Bolton,
Charles Bon
4th, 2004 Marcel Dekker
4. Essential Statistics For The
Pharmaceutical Sciences:
Philip Rowe 1st, 2007 John Wiley & Sons Ltd
5. Pharmaceutical Statistics David Jones 1st, 2002 Pharmaceutical Press UK
6. Applied Statistics And
Probability For Engineers
Douglas C M.,
Alasdair G M
Nairn, G. Runger
4th, 2006 Wilely
7 Statistics Methods S. P. Gupta 2nd , 1969 S. Chand & Co.
Title of the Course Pharmaceutics-II
Marks 50
Number of Hours per Week 2
Total Hours 30
Class F.Y. B. Pharm.
Semester II
Sr.No. Title Hrs
1. Monophasic liquid orals: Preformulation considerations 2
2. Principles of Solubilization and Taste masking 3
3. Formulation considerations in the development of Monophasic liquid oral dosage
forms and quality control of : aromatic waters, solutions, syrups, elixirs, linctuses,
drops, glycerites, paints, lotions, liniments, sprays. examples of official
preparations belonging to this class.
10
4. Large scale manufacture and packaging 2
5. Biphasic disperse systems: Suspensions: Preformulation considerations and
Physicochemical principles underlying the formulation of suspensions including
principles of wetting, Zeta potential etc.
4
6. Formulation considerations in the development of suspensions for internal and
external use and quality control - examples of official preparations belonging to
this class.
5
7. Large scale manufacturing, packaging 3
8. Layout design of liquid section. 1
19
Books Recommended
Sr.No. Title Author/Editor Edition Publisher
1 Pharmaceutical Dosage Forms
And Drug Delivery Systems
Howard C. Ansel,
Nicholas G.
Popovich, Loyd
V.
6th , 1995 B.I. Waverly Pvt.Ltd.,
New Delhi
2 Remington’s-The Science And
Practice Of Pharmacy (Vol.1
& 2)
David B. Troy 21st, 2006 Lippincott Williams &
Wilkins
3 Dispensing For Pharmaceutical
Students
Cooper & Gunn’s
Revised By
S.J.Carter
12th, 1975 Cbs Publishers &
Distributers
4 Pharmaceutics:The Science Of
Dosage Form Design
Michael E.Aulton 6th, 1998 Churchill-Livingstone
5 Physical Pharmacy-Physical
Chemical Principles In
Pharmaceutical Sciences
Alfred
N.Martin,James
Swarbrick,Arthur
Cammarata
2nd, 1969 Lea &
Febiger,Philadelphia
6 Theory & Practice Of
Industrial Pharmacy
Leon
Lachman,Herbert
A.Lieberman &
Joseph Kanig
2nd , 1976
3rd , 1987
Lea & Febiger,
Philadelphia
7 Prescription Pharmacy Goseph. B.
Sprowls
2nd , 1970 -
8 Bentley’s Textbook Of
Pharmaceutics
Bentley 8th , 1977 E. A. Rawlins
9 Introduction Of
Pharmaceutical Dosage Forms
Howard Ansel 3rd , 1981 Lea & Febiger
Title of the Course Pharmaceutical Engineering-II
Marks 50
Number of Hours per Week 2
Total Hours 30
Class F.Y. B. Pharm.
Semester II
Sr.No. Topic Hrs.
1. Fluidization: Particulate fluidization, aggregate fluidization- 3
2. Separation by mass transfer: Solid-liquid extraction and liquid extraction,
equipment and methods of operation- distillation, batch fractionation, vacuum and
still distillation, azeotropic and extractive distillation, fractional distillation and
fractionating columns; Recovery of solvents.
6
3. Energy and mass transfers: Crystallisation-crystal shapes and habits, crystal
growth, crystallisation in melts, nucleation, crystallisation from solutions, rate of
crystallisation,
5
20
4. .Energy effect in the process, size of crystal, different crystallisers, principles
underlying the design and operations;
4
5. Theories of Absorption and adsorption, Absorption of gases in liquids, Adsorption
of liquids on carriers
6
6. Drying: Fluid bed dryers, Microwave dryers, Freeze dryers, Spray dryers, tray
dryer, tunnel dryer, turbo dryer
6
Books Recommended
Title of the Course Physical Pharmacy-I
Marks 50
Number of Hours per Week 2
Total Hours 30
Class F.Y. B. Pharm.
Semester II
Sr.No. Topic Hrs
1. State of matter: Gases: Ideal and Nonideal gases, van der Waals equation, critical
phenomenon, determination of gas constants, liquefaction
5
2. Thermodynamics: first law, second law, third law, thermochemistry, free energy
function and its applications, chemical potential, Clausius-Clapeyron equation, free
energy and equilibrium, the van’t Hoff equation
5
3. Physical properties of Drug Molecules: Dipole moment and its determination,
refractive index and molar refraction, viscosity.
4
4. Solutions of Nonelectrolytes: Units for expressing concentration and calculations
involving the same, ideal and real solutions, Raoult’s law, Henry’s law
5
5. Colligative properties, elevation of b.p., depression of freezing point, osmotic
pressure, molecular weight determination based on colligative properties, molecular
weight by steam distillation.
5
6. Solution of electrolytes: Properties of solutions of electrolytes, Arrhenies theory of
electrolytic dissociation, theory of strong electrolytes, coefficients for expressing
colligative properties.
6
Sr.No. Title Author/Editor Edition Publisher
1 Introduction to
Chemical
Engineering
Walter L.Badger, Julius
T. Banchero
International
Student Edi.
McGraw Hill Book
Company
2 Perry’s Chemical
Engineer’s Handbook
Perry Robert H.
Green Don W.
7th, 1997 McGraw Hill Book
Company
3 Tutorial Pharmacy J.W. Cooper, Colin
Gunn
4th, 1950 Sir Isaac Pitman &
Sons,London
4 Introduction to
Pharmaceutical
Engineering
A.R. Paradkar 6th, 2004 Nirali Prakashan
21
Books Recommended
Sr.No. Title Author/Editor Edition Publisher
1 Physical Pharmacy-Physical
Chemical Principles in
Pharmaceutical Sciences
Alfred N. Martin,
James Swarbrick,
Arthur Cammarata
2nd, 1969 Lea & Febiger,
Philadelphia
2 Tutorial Pharmacy J.W. Cooper, Colin
Gunn
4th, 1950 Sir Isaac Pitman &
Sons Ltd.,London
3 Essentials of Physical
Chemistry
Bahl B.S. 23rd S.Chand & Sompany
4 Remington’s-The Science
and Practice of
Pharmacy(vol.1 & 2)
David B. Troy 21st, 2006 Lippincott Williams &
Wilkins
Title of the Course Anatomy, Physiology & Pathophysiology-II
Marks 50
Number of Hours per Week 2
Total Hours 30
Class F.Y. B. Pharm
Semester II
Sr.No Topic Hrs.
1 Muscular system: Anatomy-Physiology of smooth and skeletal muscles
Physiology of NMJ, Skeletal muscles contraction, energy metabolism, types of
contraction of muscles.
Definition: Myasthemis gravis, tetanus, spasticity.
10
2 Physiology of pain: Headache, Types of Headache (migraine, tension headache,
headache affecting elderly)
Joint pain (RA/Osteoarthritis/gout)
2
3 Reproductive System: Anatomy- Physiology of male and female reproductive
system, Menstruation, oocytogenesis, spermatogenesis.
5
4 Endocrine system: Anatomy- Physiology of pituitary, thyroid, parathyroid, adrenal,
pancreas, testis, ovaries, control of hormone secretion. Diseases associated with
hypo-hypersecretion of hormones.
Pathophysiology of Diabetes Mellitus
13
Books : Same as under Anatomy, Physiology and Pathophysiology-IV
22
Title of the Course Pharmaceutical Analysis-I
Marks 50
Number of Hours per week 2
Total Hours 30
Class F. Y. B.Pharm.
Semester II
Sr.
No.
Topic Hrs.
1. Introduction:
a. Significance of quantitative analysis in quality control, different
techniques of analysis, preliminaries and definitions, types of errors,
selection of sample, precision and accuracy.
b. Fundamentals of volumetric analysis, methods of expressing concentrations, primary
and secondary standards. Calculation of equivalent weight and stoichiometry.
3
2. Aqueous Acid-Base titrations:
a. Law of mass action, hydrolysis of salts, neutralization curves, and
theory of indicators, choice of indicators, mixed indicator.
b. Application** in assay of Benzoic acid, Boric acid, Aspirin.
4
3
3. Non-Aqueous titrations:
a. Types of solvents, end point detection,
b. Application** in assay of Sodium acetate, Sodium benzoate, Norfloxacin tablet.
3
4. Oxidation-Reduction titrations:
a. Theory of redox titration, measurement of electrode potential,
oxidation-reduction curves, redox Indicators.
Titrations involving
b. Potassium permanganate, potassium dichromate, potassium
bromate, potassium iodate, cerium (IV) sulfate, Iodine (Iodimetry
and Iodometry), titanous chloride.
c. Applications** in assay of Ferrous sulfate, Ascorbic acid, Isoniazide, Hydrogen
peroxide.
5
5. Complexometric Titrations:
a. Theory, formation of complex and its stability, titration curves,
metallochrome indicators, types of EDTA titrations,
b. Application** in assay of Magnesium sulfate, Lead nitrate and calcium gluconate.
3
6. Argentometric Titrations:
a. Theory, factors affecting solubility of a precipitate, titration methods-
Mohr’s, Volhard’s, Gay lussac, and Fajan’s method, indicators.
b. Applications** in assay of Potassium chloride, Sodium chloride and
Ammonium chloride.
3
7. Miscellaneous methods of analysis:**
a. Diazotisation titrations,
b. Kjeldahl’s method of nitrogen determination
c. Oxygen flask combustion method.
3
23
8. Gravimetric analysis:
a. Precipitation techniques, solubility products, colloidal state,
supersaturation, co-precipitation, post precipitation, digestion, filtration,
ignition, weighing and calculation.
b. Application** in assay of Alum by oxime reagent, Calcium as calcium oxalate and
magnesium as magnesium pyrophosphate.
3
**Applications should cover all different techniques and methods and may also include
other compounds to which the techniques are applicable.
Books Recommended
Sr.No. Title of the Book Author/Editor Edition/
Year
Publisher
1. Vogel’s Textbook of
Quantitative
Inorganic Analysis
Bassett J, Denny R
C, Jeffery G H,
Mendharn J,
7th , 1998 ELBS/Longman, London.
2. Statistical Quality control
6. Instrumental methods
of Analysis- Ewing.
Grant 6th , 1988 McGraw Hill
3. A Textbook of
Pharmaceutical Analysis,
Connors K A 3rd , 1982 Wiley Interscience, New
York.
4. Practical Pharmaceutical
Chemistry Vol. I
Beckett A. H. and
Stenlake J B,
4th , 1988 TheAnthlone Press of
University of London.
5. Analytical Chemistry an
Introduction,
Skoog/ West/
Holler
4th , 1986 CBS Publications, Japan
6. The Quantitative
Analysis of Drug
Garrat 3rd , 2005 Toppan & Co.
7. Analytical Chemistry Gary Christian- 3rd, 1971 John Wiley
8. IP, BP, USP, EP and
International
Pharmacopoeia.
Current
Editions
24
Title of the Course Assignments (Pharmaceutical Engineering)
Marks 50
Number of Hours per week 2
Total Hours 30
Class F. Y. B.Pharm.
Semester II
Sr. No. Topic
1. There will be several problem solving sessions where there will be discussions on
methodology and approaches to solve problems including discussions on how to gather
information from internet and literature. The problems will be given to the students as
home assignments where students can go through the literature and come out with
solutions and present it in the class. There shall be many assignments. No assignment shall
be of more than 10 marks. The student shall submit the assignment in A4 size paper either
hand written or typed and pinned together. Marks will be awarded by the teacher and at
the end of the semester teacher will submit the marks along with the assignment copies of
all the students to the office.
Laboratory
Title of the Course Organic Chemistry Laboratory-II
Marks 50
Number of Hours per Week 4
Total Hours 60
Class F.Y. B.Pharm
Semester II
Sr.No Experiment Hrs.
Techniques in Organic Chemistry:
1 Qualitative separation of binary organic mixture by physical and chemical methods
-mixture of different types including compounds with more than one functional
group to be given, characterization of individual components by physical constants;
followed by preparation of suitable derivative;
16
2 testing purity by TLC. 4
3 Purification techniques
solvent sélection for recristallisation, recristallisation techniques
simple distillation, fractional distillation, steam distillation.
16
16
4 Exercises 8
Books Recommended Will be recommended by the teachers
25
Dostları ilə paylaş: |