Dementia
Dementia is a term used to
describe a group
of symptoms affecting memory, thinking
and social abilities severely enough to
interfere with your daily life. It isn’t a
specific disease, but several diseases can
cause dementia.
Though dementia generally involves
memory loss,
memory loss has different
causes. Having memory loss alone doesn’t
mean you have dementia, although it’s often
one of the early signs of the condition.
Alzheimer’s disease is the most common
cause of a progressive dementia in older
adults, but there are a number of other
causes of dementia. Depending on the cause,
some
dementia symptoms might be
reversible.
Symptoms
Dementia symptoms vary depending on the
cause, but common signs and symptoms
include:
Cognitive changes
Memory loss, which is usually noticed by
someone else
Difficulty communicating or finding words
Difficulty with
visual and spatial abilities,
such as getting lost while driving
Difficulty reasoning or problem-solving
Difficulty handling complex tasks
Difficulty with planning and organizing
Difficulty with coordination and motor
functions
Confusion and disorientation
Psychological changes
Personality changes
Depression
Anxiety
Inappropriate
behavior
Paranoia
Agitation
Hallucinations
Types of dementia include:
Alzheimer’s disease, the most common
dementia diagnosis among older adults. It is
caused by changes in the brain, including
abnormal buildups of proteins known as
amyloid plaques and tau tangles.
Frontotemporal dementia,
a rare form of
dementia that tends to occur in people
younger than 60. It is associated with
abnormal amounts or forms of the proteins
tau and TDP-43.
Lewy body dementia, a form of dementia
caused by abnormal
deposits of the protein
alpha-synuclein, called Lewy bodies.
Vascular dementia, a form of dementia
caused by conditions that damage blood
vessels in the brain or interrupt the flow of
blood and oxygen to the brain.
Mixed dementia,
a combination of two or
more types of dementia. For example,
through autopsy studies involving older
adults who had dementia, researchers have
identified that many people had a
combination
of brain changes associated
with different forms of dementia.
Treatment:
Cholinesterase inhibitors. These medications
— including donepezil (Aricept),
rivastigmine (Exelon) and galantamine
(Razadyne)
Memantine. Memantine (Namenda) works
by regulating the activity of glutamate,
another chemical messenger involved in
brain
functions, such as learning and
memory.