Therapeutic possibilities for the correction of cognitive and psychoemotional impairments in patients with post-covid syndrome



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Статья-скопус-Уринов-Р. (2)

Group

Sign

A subgroup

B subgroup

Total

Main

Аbc.

36

64

100

(MG)

%

36,0

64,0

100,0

In a comprehensive clinical examination of patients, the generally accepted clinical examination of the somatic status, neurological examination using the MMSE scale, Luria’s “10 words” test, Schulte's technique were used.


The test for the study of cognitive functions - MMSE (Mini Mental Scale Examination) provides an assessment of orientation in place, time, concentration, perception, memory, speech, execution of a three-stage command, reading and drawing according to a model. The evaluation of the data obtained, expressed in points, was carried out according to a special table.
Method of “Bioacoustic correction” (BAC) implemented in the Synchro-S hardware-computer complex. Registration certificate № FSR 2010/07223 dated March 01, 2016, certificate of conformity (GOST R) No. ROSS RU.ME.HO263 dated 04.22.2013, license for the production of medical equipment № FS-99-04-004808 dated 06.28.16, patent № 2410025, 24228927, 2492839. (Fig.1).



Picture 1. Hardware-computer complex “Synchro-S”.


The Bioacoustic Correction (BAC) method was developed by neurophysiologists of the Physiological Department named after A.I. I.P. Pavlov FGBNU “IEM” (group of neurodynamic correction of the pathology of brain functions). The physiological basis of the BAC method is sensory EEG-dependent stimulation. This method uses various acoustic (musical, verbal and other) stimuli synchronized and consistent with the current bioelectrical activity of the brain and presented to the patient in real time, that is, the patient is presented with an acoustic image of his own EEG in real time. Important adjustable parameters for presenting this image are: sound volume (set separately for each EEG channel), type of sound (vocal, instrumental, formant, verbal), exposure intensity (selected from 10% to 100% - sets the level of correlation of acoustic stimuli with the original EEG), procedure duration (from 1 to 25 minutes).
The patient listens to the acoustic image of his own bioelectrical activity of the brain for a set time, with other set parameters. The patient does not receive any cognitive tasks for voluntary control of the presented acoustic stimuli and control of his own functional state. The only task of the patient is to listen to the presented sounds. However, the level of attention to the presented acoustic image is not a key condition for BAC procedures, which makes it possible to use the method regardless of the age and degree of preservation of the patient's cognitive functions. BAC has a number of advantages over other types of treatment: non-drug and non-invasive treatment of functional disorders of the central nervous system; lack of addiction, side effects and age restrictions; compatibility and acceleration of other types of treatment, reduction of drug load, with some nosologies, the possibility of replacing drug treatment. Each BAC procedure is controlled by EEG recording on 4 channels in on-line mode (review and indexometric analysis). After each procedure, it is possible to evaluate the change in various EEG parameters (indexometric, pattern, cross-correlation and other types of mathematical analyzes).

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