Clinical and prognostic significance of hepatitis b rna in chronic viral hepatitis B


Samples with confirmed occult hepatitis (sequence) cccDNA, samples collected in 2018



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Samples with confirmed occult hepatitis (sequence) cccDNA, samples collected in 2018

No test tubes

No sample

AmpliSense HBV-FL

ROSSAmed HBV-RNA

CT yellow

CT green

1

31

neg

neg

20,41

2

22

neg

neg

21,45

3

28

neg

32,72

22,29

4

197

neg

neg

20,16

5

193

neg

neg

20,1

6

32

neg

neg

21,51

7

45

neg

neg

21,07

8

44

neg

neg

20,61

9

38

neg

neg

20,33

10

62

neg

neg

21,3

11

58

neg

neg

21,54

12

36

neg

neg

20,13

13

K+


16,43

17,8




Key words : HBV RNA , intrahepatic cccDNA , occult hepatitis, chronic hepatitis B


Table No. 2Test results of patients with clinical manifestations of hepatitis, unclear etiology

Group 2, there are clinical manifestations of hepatitis, but no markers (2022)

№№ test tubes

№№ sample

Ample sense HBV-FL

ROSSAmed HBV-RNA

CT yellow

CT green

1

Л1

neg

neg

27,6

2

Л2

neg

neg

24,19

3

Л3

neg

neg

25,38

4

Л4

neg

neg

23,12

5

Л5

neg

neg

26,38

6

Л6

neg

neg

22,87

7

Л7

neg

neg

22,73

8

Л8

neg

neg

25,34

9

Л9

neg

neg

23,71

10

Л10

neg

23,93

23,97

11

Л11

neg

neg

25,65

12

Л12

neg

neg

23,46

13

Л13

neg

neg

24,45

14

В

neg

neg

21,32


Table No. 3 Results of comparative testing of samples containing hepatitis B virus DNA based on the results of the control set

№№ test tubes

№№ sample

АмплиСенс HBV-FL (образцы содержащие ДНК ВГВ)

IFA

Ample sense HCV-FL

ROSSAmed HBV-RNA (samples containing HBV DNA)

HBsAg

anti-HDV

anti-HCV

CT green

CT yellow

1

1/9

pos





22,24

5,78

2

1/14

pos





27,49

27,58

3

1/17

pos





24,7

24,62

4

1/18

pos


neg



25,34

26,24

5

1/22

pos


neg



27,56

26,54

6

1/27

pos


neg

neg


22,59

28,51

7

1/102

pos


pos



21,69

26,74

8

1/103

pos





21,76

28,91

9

1/110

pos


neg



23,08

23,93

10

1/113

pos


neg



26,37

30,45

11

1/114

pos





25,21

24,54

12

1/117

pos


neg



23,21

31,66

13

1/118

pos





25,19

28,26

14

1/119

pos





23,15

28,37

15

1/121

pos


neg



24,8

28,04

16

1/123

pos


neg



21,93

28,51

17

1/128

pos

pos

neg



24,85

28,57

18

1/130

pos

pos

neg



25,83

29,36

19

1/133

pos


neg



26,05

26,99

20

1/134

pos

pos

neg



24,92

31,24

21

2/122

pos




pos

21,8

27,76

22

4/2

pos





21,93

31,07

23

4/3

pos





22,96

29,23

24

4/9

pos





26,42

8,66

25

4/10

pos





21,37

8,1

26

4/17

pos


neg



26,43

30,97

27

4/44

pos


neg



22,78

29,4

28

4/144

pos





22,85

26,14

29

4/147

pos





22,64

27,45

30

4/148

pos





22,57

28,76

31

2/1

pos


neg



24,93

27,79

32

2/2

pos


neg



24,06

27,2

33

2/3

pos





23,95

19,42

34

2/5

pos





20,52

29,33

52

28/28

pos




neg

22,74

29,58

53

28/152

pos




pos

19,08

28,73

54

29/106

pos




pos

21,25

30,04

55

29/133

pos




pos

19,96

28,42

56

1/4

neg 



 pos

neg

20,79


57

14/153

neg 



 pos

neg

20,89


58

oko






20,82


59

pko






21,81

21,9

60

k+






17,87

16,59


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