Biotop-report 2014
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- Biotech Companies
57 BioTOPics 47 | May 2014 BioTOP-Report Addresses Biotech Companies PolyAn, Gesellschaft zur Herstellung von Polymeren für spezielle Anwendungen und Analytik mbH PolyAn is specialised in Molecular Surface Engineering (MSE). Using our surface modi- fication expertise PolyAn optimises the performance of analytical systems by improving the signal-to-noise ratio as well as the reproducibility of consumables for multiplex diag- nostics, LifeScience research and screening applications. PolyAn?s product portfolio includes functionalised microarray slides, microparticles for multiplex bead arrays and functionalised membranes for medical diagnostic applications. poly-an.de Preclinics Gesellschaft für präklinische Forschung mbH Preclinics is a commercial cooperation partner for preclinical research and develop- ment. As a competent, creative and experienced partner preclinics investigates phar- maceutical substances, therapeutic methods and proceedings as well as medical products during the preclinical phase. Additional we provide custom antibody produc- tion in llama, goat, sheep, rabbit and other species. preclinics.com Predemtec GmbH Predemtec GmbH is a company focused on the research, development and manu- facture of innovative diagnostic tests for use in the detection of dementia-related risk factors. The goal has been to make the early and reliable diagnosis of various demen- tia-related illnesses a reality through the use of our innovative diagnostics tests. predemtecDX.com ProBioData GmbH BioProcessDB is a database solution for bioprocess R&D. It's designed to become the linking tool in your information process and to integrate the data i. e. from the SCADA system, the sample data management and the strain management. probiodata.de ProBioGen AG ProBioGen is a Contract Development and Manufacturing Organization (CDMO) and Technology Provider, with extensive expertise in cell line engineering, process devel- opment (upstream- and downstream process) and GMP manufacturing of biopharma- ceuticals. Offering state-of-the-art contract development and manufacturing services as well as access to proprietary cell lines (AGE1.cell lines ® ) for the manufacturing of biopharmaceuticals and vaccines. The company possesses the manufacturing autho- rization from the competent authority and meets the quality standards required by the EMA and the FDA guidelines. probiogen.de ProteaImmun GmbH ProteaImmun is a specialized proteomic company providing purified human proteins, antibodies and ELISAs. Our proteins are designed for structural and functional stud- ies of proteases screening and evaluation of protease inhibitors and modulators. Fur- thermore we develop highly sensitive ELISA kits and antibodies. Our Focus: MMPs, ADAMTs, HtrAs. ProteaImmun produces a unique range of recombinant proteases for medical and pharmaceutical research. The main focus is on human Matrix Metallo- proteases (MMPs), ADAMTS and HtrA proteins which play an important role in neuro- degenerative disease, ancer and arthritis. Customer Service: ProteaImmun provides activity analysis by zymography adapted for MMPs. proteaimmun.net PROTEKUM - Umweltinstitut GmbH, Oranienburg We plan to eliminated fluid und solid waste products in a manner which is compatible with environment protection. Our methodology is largely based on painstaking analysis. We use modern equipment and scientific methods. Protekum offers high-quality prod- ucts and services in environmental analysis redevelopment. protekum.de Proteome Factory AG Biomarker & target discovery, validation, analysis of food and ingredients, absolute quantification of proteins and peptides, sequencing and characterization of proteins and antibodies (CDR), 2DE and LC-MS based proteomics studies, pharmacokinetics, pharmaco, immuno and membrane proteomics, protein identification, characterization of proteins and peptides (PTMs, e.g. phosphorylation, glycosilation), quality control, mass determination, N-terminal amino acid sequencing, silver staining kit etc. proteomefactory.com Provitro GmbH Provitro combines more than ten years of experiences in commercialisation of cell culture technologies, Tissue Microarrays and immunohistochemical analyses with the scientific expertise of the Pathological Institute of the Charité, Berlin. Based on a quality management system according to ISO 9001:2008, we provide our customers not only with high-quality products, CE marked in vitro-diagnostics and state-of-the-art services but also with individual solutions for their specific requests. provitro.de Rapidozym Gesellschaft für Laborhandel und DNA Diagnostika mbH Expertise of cell biologists cell manufacturing and clean room technology specialists. Focuses on clinical stem cell product development portfolio are stroke, myocardial in- farction and plastic surgery. rapidozym.de RENESA UG (haftungsbeschränkt) Manufacturing and distribution of rapid tests, mainly for medical purposes (Point of Care Testing). renesa.de RiNA GmbH RiNA has developed systems for cell-free protein biosynthesis based on pro- and eu- karyotic cell lysates. A synthesis service is realised in RiNA’s own laboratories and complements the EasyXpress Kits (Qiagen). The purchase of Roche´s RTS-products enables RiNA now to be a key player in the field of cellfree biosynthesis with a large variety of products. Another research focus is the development of aptamers (DNA and RNA) for biosensors. rina-gmbh.eu RIPAC-LABOR GmbH RIPAC-LABOR offers high-quality diagnoses of bacterial infections, particularly in poul- try, pigs and cattle, but also in other farm and domestic animals. The company uses pathogen differentiation to provide quick and effective methods for fighting pathogens. It performs resistance tests and epidemiological analyses and also focuses on produc- ing herd-specific vaccines. ripac-labor.de Roboklon GmbH Distribution, Marketing and Development of Products for Molecular Biological Research and Genetic Engineering. roboklon.de
58 BioTOPics 47 | May 2014 BioTOP-Report Addresses Biotech Companies ROVALAB GmbH Our Master Mixes for QPCR, Standard-, Hot Start- and High Fidelity PCR as well as our high quality critical raw materials and reagents such as DNA Polymerases and dNTPs are designed to help you successfully and rapidly solve your scientific and manufac- turing tasks. rovalab.com Royal Biotech GmbH Royal focuses on developing, manufacturing and marketing innovative kits, portable or micro-structured systems, and the next generation of diagnostic chips for near re- al-time environmental, food safety, disease and laboratory diagnostics. royalbiotech.com Scienion AG Scienion is a life science company in the markets of dispensing systems and microar- ray technologies. The product portfolio comprises hardware, consumables and ser- vices. Scienion’s leading product is the sciFLEXARRAYER dispensing system, available in a product line of six size versions. The dispenser allows the aspiration of ultra low liquid volumes from different reservoirs and non-contact micro drop delivery in the picoliter to microliter range onto a variety of carriers. scienion.de Sepiatec GmbH Production, development and sales of automated HPLC machines for high-throughput purification and fractioning of complex substance compounds. sepiatec.com Seramun Diagnostica GmbH Seramun offers peptide synthesis, purification and conjugation of proteins, production of antibodies, customer research, in vitro-Diagnostics. We focus on the development and production of enzyme immunoassays for diagnosis of viral and bacterial infections and autoimmune diseases of the gastrointestinal tract, the development of multi-pa- rameter assays as microtitre plate assays and as membrane immunoassays, as well as development of ready-to-use substrate solutions and for protein stabilizers. seramun.com SGS INSTITUT FRESENIUS Berlin GmbH & Co. KG Analytical laboratory services and consulting for development, production and quality control of drugs. institut-fresenius.de SIFIN Institut für Immunpräparate und Nährmedien GmbH Berlin Development, production and purification of monoclonal antibodies for use in diag- nostics. Development and production of blood grouping reagents, Serafol ® bedside cards and test reagents for serotyping of Salmonellae, Shigellae, E. coli and Yersiniae. Development and production of culture media for microbiological diagnosis. sifin.de Signature Diagnostics AG Signature Diagnostics is dedicated to the discovery, validation and commercial de- velopment of novel diagnostic products that predict outcome and drug response in patients with colorectal cancer (CRC), non-small cell lung cancer (NSCLC) and ovarian cancer. Signature believes that patient selection and stratification based on molecular gene signatures will soon become an important component of routine cancer treatment. signature-diagnostics.de Silence Therapeutics AG Silence Therapeutics AG is a leading RNAi therapeutics development company and offers a novel, proprietary siRNA technology (AtuRNAi) and proprietary systemic de- livery systems for siRNA (AtuPLEX, DACC and DBTC). SILENCE pipeline consists of both partnered and internal programs of which 3 clinical phase II and 1 clinical phase I programs are partnered with Pfizer/Quark (2 ophthalmic indications) and Novartis/ Quark (2 kidney indications). Silence?s internal lead compound Atu027 is currently in a Phase I clinical study for the treatment of solid tumours. silence-therapeutics.com SINA Science Services GmbH SINA is a modern company providing elaborate services in molecular biology and protein biochemistry. Together with our industrial partners and customers from re- search institutions we develop complex cloning and mutagenesis strategies including high-throughput applications. We offer cloning of genes, expression and purification of proteins, DNA and RNA isolation from numerous biological materials and the production of competent cells with high transformation efficiency. sina-science-services.de SLM- Speziallabor für angewandte Mikrobiologie GmbH Microbiological quality control for medical devices, pharmaceuticals, cosmetics, drink- ing water, foodstuff, monitoring in clean rooms. speziallabor.com Sopat GmbH SOPAT is specialized in the analysis of particulate systems. The company develops and markets an innovative particle measurement technology for real-time analysis of multi- phase systems. Particles, such as droplets, grains, cells or bubbles, are measured with high precision in running processes. sopat.de
STRATEC Molecular GmbH STRATEC Molecular GmbH is a globally active provider of innovative system solutions for nucleic acid sample collection, stabilization, and both manual and automated puri- fication from any sample type. Since 1992 the company is internationally respected for its outstanding and high performance technology platforms and offers a broad spec- trum of superior products for molecular diagnostics, drug discovery and Life Science research. invitek.de Strix Diagnostics GmbH Strix Diagnostics is a medical diagnostics company specializing in customized devel- opment of certified analytical systems for multiparameter in vitro-diagnostics. strix-diagnostics.de Surflay Nanotec GmbH Surflay Nanotec GmbH, a spin-off company from Capsulution NanoScience AG, is spe- cialized on coating colloidal and planar materials with functional films. Key technology is the patented LbL-Technology ® with polymers. Applications are in the fields of separa- tion materials, pigment encapsulation, bio-sensing and diagnostic particles. In addition to customer tailored projects Surflay offers an unique range of products of tunable multifunctional nano-or microparticles and dye-labeled polymers. surflay.com 59 BioTOPics 47 | May 2014 BioTOP-Report Addresses Biotech Companies t-cell Europe GmbH t-cell Europe GmbH, a spin-off of the Berlin Brandenburg Center for Regenerative Med- icines (BCRT), is aiming to become the world’s technology leader in the application of T-cell-based therapies used in transplantation medicine. Over the next few years, with its three proprietary platform technologies, the company will develop and clinically validate novel T-cell-based products and corresponding diagnostics to regulate the immune system and treat viral infections. The company’s lead reference product will be a first-in-class Treg cell product/therapy for kidney transplantation that suppresses organ rejection in recipients t-cell.de Thanares GmbH Development, use and marketing of analytical process for diagnostic and therapeu- tic purposes. Future business activities: detection process for bioactive substances in bodily fluids, isolation, characterization and investigation of bioactive compounds from plants, in particular insoluble proteins or low concentrations of proteins, development of low cost genetic systems for over-expression and/or production of such proteins. thanares.com TheraKine BioDelivery GmbH Development of antibody drug delivery systems and related tasks. therakine.com Thermo Fisher Scientific – B·R·A·H·M·S GmbH Thermo Scientific Biomarkers (B·R·A·H·M·S GmbH) explores, develops and produces new diagnostic test procedures to improve the diagnosis, and thereby the treatment, of life-threatening illnesses. This takes place with over 470 employees, in the disease ar- eas infectiology, cardiology and pneumology as well as thyroid, autoimmunity and car- diology on the basis of our own patented biomarkers. Since October 2009 B·R·A·H·M·S GmbH is part of Thermo Fisher Scientific Inc. (NYSE: TMO), the world leader in serving science.
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TIB MOLBIOL Syntheselabor GmbH
In 1990, TIB MOLBIOL became the first German manufacturer of oligonucleotides. In addition to designing and synthesizing primers and probes for Real-Time PCR assays, we develop and produce LightMix ® Kits for Roche Diagnostics LightCycler ® Instruments, covering applications in Clinical Chemistry, Pharmacogenetics, Pathogen Detection, as well as Cancer Research. TIB MOLBIOL is ISO 13485 and ISO 9001 certified. tib-molbiol.com TissUse GmbH TissUse is a vibrant growth company providing high-value services in the area of tissue culture analysis of drug candidates, cosmetics, chemicals and consumer products. tissuse.com TransTissue Technologies GmbH TransTissue has been a subsidiary of BioTissue Technologies, Freiburg since Septem- ber 2001. With more than 15 years of experience in regenerative medicine, the scien- tists of TransTissue Technologies have developed second-generation autologous tissue replacements, e.g. cartilage and bone grafts. We are mainly concerned with inventions and the development of tissue engineering products for regenerative medicine. We offer a broad panel of services in the field of regenerative medicine. transtissue.com UGA Biopharma GmbH UGA Biopharma a private Research and Development company, focuses on Research, Development and Commercialization of Biopharmaceutical products under contract with other Biopharmaceutical companies. UGA Biopharma conducts power of biosci- ences to develop high-tech, last generation of biomedicine, diagnostic kits, molecular biology items and also offers world class services in biotechnology area. ugabiopharma.com Umwelttechnik-Berlin UG Feasibility studies, development, planning, construction and operation of biotechno- logical plants for groundwater, process water and waste water purification. Accredited microbiological laboratory for the investigation of drinking water, groundwater, bath water, soils, food, anti-microbial active ingredients and sterility according to Ph.Eur, approved in accordance with BiostoffV and the German infection protection act (Infek- tionsschutzgesetz). bartetzko.com Zellwerk GmbH Zellwerk produces the proprietary Z ® RP cell cultivation system, comprising rotating bed bioreactor, GMP Breeder, Control Unit, software. Bioreactors with 50-5000 ml vol- ume, 0,2-2 m² seeding surface, different cell carriers, can be delivered. In this culturing system cells grow tissue-like, being embedded in self-generated extra-cellular matrix. The technology opens unique opportunities for the GMP-compliant expansion of stem cells and primary cells, manufacturing of cell-seeded implants as well as production of recombinant proteins. In addition, we have recently developed a new bioreactor for expansion of immune cells for cell therapy of leukemia and several types of cancer. zellwerk.biz Zentrum für molekulare Onkologie GmbH Innovative methods for diagnostic and therapy of tumor diseases - Molecular genetics (K-RAS, PCA3, Septin9, ...) - Chemoresistance assay for prediction of chemotherapy - Pathology Development of new biomarkers and analytical services for studies. molekulare-onkologie.eu Zytomed Systems GmbH Zytomed Systems´ focus is the development, production and distribution of antibod- ies and detection systems for immunohistochemical cancer diagnostics as well as re- agents and kits for in-situ hybridisation. zytomed-systems.de
BioTOP is a joint initiative of the state of Berlin and the state of Brandenburg under the umbrella of the Berlin Partner für Wirtschaft und Technologie GmbH and takes part in the Cluster Management HealthCapital. BioTOP is funded by the federal state of Berlin, the federal state of Brandenburg and the Investitionsbank Berlin, co-funded by the European Union (European Fund for Regional Development). Investing in your Future Document Outline
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