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BioTOPics 47 | May 2014
BioTOP-Report 2014
Evestra GmbH
Evestra GmbH, founded in July 2008, is a
fully owned subsidiary of Evestra Inc. located
in San Antonio Texas. Evestra GmbH serves
as the development and commercialization
center for Europe and ROW. Evestra’s mis-
sion is to develop and commercialize steroid-
based female healthcare products. The
development strategy of the company
includes product ideas with known com-
pounds as well as New Chemical Entities.
Evestra is conducting research and product
development in a number of in-demand, but
as yet unmet, medical need areas of wom-
en’s health such as hormonal-dependent
breast cancer and endometriosis. The com-
pany is also pursuing different projects in
fertility control, e.g. a new estrogen for oral
contraception, with superior pharmacologi-
cal properties compared to the standard
drug ethinyl estradiol.
Several patents on new composition of mat-
ter, new technical processes and use patents
have been filed during the last years and
support the strong intellectually property
position. Evestra is concentrating on R&D
and will seek more partners for commercial-
ization.
More detailed information can be found on
our website.
Address
Evestra GmbH
Britzer Straße 26
12439 Berlin · Germany
EU Contact
Prof. Klaus Nickisch · Managing Director
Phone +49 30 66509642
knickisch@evestra.com
www.evestra.com
LGC Genomics
At LGC we offer a full range of high quality
PCR reagents, custom genotyping assays,
genomic services and workflow solutions for
DNA sample preparation and downstream
processing (www.lgcgroup.com/genomics).
Our proprietary KASP™ allelic discrimination
chemistry and has optimised workflows for
1536 microtitre plates that enable assay min-
iaturisation for more flexible, cost-effective
workflow solutions in high-throughput geno-
typing. In addition, customers are offered
industry leading proprietary nucleic acid
extraction, sequencing and genotyping ser-
vices from our labs globally.
„We use what we sell and sell what we use”
is key to the products and services we pro-
vide.
Our portfolio includes:
k
Genotyping services, assays and
reagents
k
Sanger and next-generation sequencing
services
k
DNA and RNA extraction products and
services
k
PCR reagents and consumables
k
Laboratory instrumentation
k
Plate sealers
k
Liquid handling robots
k
High-throughput PCR thermal cyclers
k
Plate readers
We operate sales offices in the UK, Germany
and the USA, with sales representatives
throughout Europe, the USA and Australia as
well as distributors in China, Korea and other
key emerging territories.
Address
LGC Genomics GmbH
Ostendstrasse 25 · TGS Haus 8
12459 Berlin · Germany
Phone +49 30 53042200
genomics@lgcgroup.com
www.lgcgroup.com/genomics
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BioTOPics 47 | May 2014
BioTOP-Report 2014
Metanomics Health GmbH
Metanomics Health – a BASF Group compa-
ny – combines comprehensive Metabolite
Profiling (metabolomics) with biomedical
data interpretation. Metabolite Profiling is
defined as the parallel analysis of multiple
endogenous and xenobiotic metabolites in
biological systems. The core expertise of
Metanomics Health resides in discovery and
validation of biomarkers.
Technologies
k
Metabolite profiling platform with more
than 75 GC-MS and LC-MS/MS instru-
ments
k
Wide metabolite coverage via combina-
tion of unbiased and targeted platforms
k
Unique tox mode of action prediction
through MetaMap
®
Tox database
k
Excellence in systems correlation analy-
sis of complex gene function relation-
ships
k
Highly robust and reproducible results
Major R&D-Topics
In cooperation with academic institutes and
clinical experts Metanomics Health is run-
ning a large-scale diagnostic biomarker pro-
gram. Areas include metabolic syndrome,
heart failure, prostate cancer and pancreatic
cancer to mention a few.
Market Segments
Metanomics Health provides its services to
pharmaceutical, diagnostics and nutrition
companies. Technology applications include:
k
Mechanism of action studies
k
Mechanism of toxicity studies
k
Translational and clinical biomarker
development (e.g. PK/PD, patient stratifi-
cation, efficacy and safety markers)
k
Companion diagnostic development
k
Cell culture & bioprocess optimization
k
Biospecimen quality control
Address
Metanomics Health GmbH
Tegeler Weg 33 · 10589 Berlin · Germany
Contact
Dr. Tim Bölke · Managing Director
Phone +49 30 34807 400
Fax
+49 30 34807 401
company.info@metanomics-health.de
www.metanomics-health.de
nanoPET Pharma GmbH
nanoPET is a biopharmaceutical company
specialized on R&D, manufacturing and mar-
keting of innovative drug substances for
Diagnostic Imaging. We focus on relevant
cardiovascular, oncological and neurological
indications as well as on regenerative medi-
cine. Nanotechnology is a key element of our
business. We operate in three major areas.
The first nanoparticular tracers for clinical
PET: nanoPET prepares the clinical develop-
ment of its patented technology platform:
inorganic nanoparticular tracers for cell- and
molecular-specific positron emission tomog-
raphy (PET).
Viscover™ imaging agents – a landmark in
small animal imaging: As animal imaging is
rapidly gaining relevance in pharmaceutical
research, we are delighted to offer you an
exciting portfolio of specialized pre-clinical
imaging agents covering the principal imag-
ing modalities (MRI, CT, Ultrasound, Optical
Imaging, SPECT & PET). Get a detailed
insight into our product portfolio and down-
load a free copy of our imaging guide on
www.viscover.com
Consulting and Service tailored to your
needs: As a technology and service provider,
we offer our expertise to biopharmaceutical
companies and imaging equipment manu-
facturers. Our customers benefit from the
long-standing industry expertise our team
has attained in the pharmaceutical
research & development.
Address
nanoPET Pharma GmbH
Robert-Koch-Platz 4
10115 Berlin · Germany
Contact
Dr. Andreas Briel · CEO
Phone +49 30 890 49740
imaging@nanopet-pharma.com
www.nanopet-pharma.com