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Biotech Companies
Novamol GmbH
Development and manufacture of human and veterinary food supplements and health-
enhancing products
novamol.com
NOXXON Pharma AG
NOXXON Pharma is a biotechnology company developing a promising new class of thera-
peutics called Spiegelmers, which are oligonucleotides made from the L-stereoisomer of
RNA. Spiegelmers can be engineered to bind specifically to a precisely defined biological
target and have been shown to be potent inhibitors. Clinical and pre-clinical studies of
Spiegelmers to date have shown them to be exceptionally safe, well-tolerated, biologically
stable and non-immunogenic. NOXXON has three programs in development, two of which
have successfully completed their first Phase I clinical studies. The company has approxi-
mately 60 employees based at its headquarter in Berlin, Germany.
noxxon.com
NutriNeu GmbH
NutriNeu GmbH develops a new generation of pre and probiotics. First products are
based on microorganisms that were isolated with our proprietary GlycoScreen technology
(antibody directed isolation of microorganisms expressing specific carbohydrate structures).
Besides developing own products, NutriNeu GmbH offers services in the fields of micro-
biology, process development and Glycoanalytic. NutriNeu GmbH also helps customers to
investigate the probiotic properties of their microorganisms.
OpTricon Entwicklungsgesellschaft f. optische
Technologien
OpTricon develops and produces mobile readers for quantitative analyzes of Immunoas-
says for Point-of-Care-diagnostics, especially Lateral Flow Assays (LFA). Additional business
segments are components and Systems for signal transmission and sensors for lbioanalyt-
ics. opTricon develops the devices in partnership with the customers and works as OEM-
suppliers and is certified by TÜV Rheinland according EN ISO 13485:2003+AC: 2007 and EN
ISO 9001:2008.
optricon.de
ORGANOBALANCE GmbH
ORGANOBALANCE is a company specializing in microbial strain development and screen-
ing. As a R&D contractor ORGANOBALANCE develops new biological products in the areas
of nutrition, personal care and health care. The company draws on its own collection of
microbial strains suitable for food applications and its OASSYS
®
bioassay systems. In the
field of ?metabolic engineering? ORGANOBALANCE exploits Saccharomyces cerevisiae yeast for
synthesis of substances for the industrial and pharmaceutical industry.
organobalance.com
ORGANOBALANCE Medical AG
ORGANOBALANCE Medical AG funds and promotes the research and development of novel
therapies based on specific probiotic cultures, aiming to develop active substances and
mechanisms for innovative medicinal products and medical devices, as well as offer new
therapeutic concepts for hitherto inadequately treatable indications.
organobalancemedical.com
ovalehn GmbH
Production and application of specific recipes -containing IgY for diagnostics and oral,
passive immune therapy
ovalehn.de
Pentracor GmbH
In the case of cardiac infarction, C-reactive protein (CRP) results in an increase of the
primary damage. Based on a new prototype, the company Pentracor GmbH aims to develop
an adsorber for therapeutic reduction of CRP, lead it to approval, establish its certified
production and market the product after clinical validation.
pentracor.com
Peptides&elephants GmbH
Custom synthesis of peptides and peptide libraries. Development parallel Synthesis tech-
nologies. Distributor of Peptide Synthesis Automation.
peptides.de
PharmaSol GmbH
Modification of ingredients or introduction of new metabolic pathways in plants with
gene-technology methods
pharmasol-berlin.de
PlasmaChem GmbH
PlasmaChem GmbH is an innovative R&D and manufacturing company specializing in
nanomaterials, plasma- and ultra-thin film technologies. The company manufactures
nano-coated medical implants (stents), nanomaterials, additives for metal plating (applied
e. g. by Siemens AG), new additives to engine oils on the base of nanodiamonds and other
industrial nanoproducts.
plasmachem.com
PolyAn, Gesellschaft zur Herstellung von
Polymeren für spezielle Anwendungen und
Analytik mbH
PolyAn is specialised in Molecular Surface Engineering (MSE) and Surface Molecular Imprint-
ing (SMI). PolyAn's proprietary MSE-technology platform is used for the production of
microarray slides, e. g. for oligo-, peptide or protein arrays. For multiplex-bead arrays Poly-
An has developed a range of functionalised, fluorescence encoded PMMA microparticles.
poly-an.de
Preclinics Gesellschaft für präklinische
Forschung mbH
Preclinics is a commercial cooperation partner for preclinical research and development.
As a competent, creative and experienced partner preclinics investigates pharmaceutical
substances, therapeutic methods and proceedings as well as medical products during the
preclinical phase.Additional we provide custom antibody production in llama, goat, sheep,
rabbit and other species.
preclinics.com
ProBioGen AG
ProBioGen is a specialist in mammalian cell development, process engineering and GMP
manufacturing of biopharmaceutical drug substances. Offering state-of-the-art contract
development and manufacturing services as well as access to proprietary cell lines (AGE1.
cell lines(R)) for the manufacturing of biopharmaceuticals and vaccines.
The company
possesses the manufacturing authorisation from the competent authority and meets the
quality standards required by the EMEA and the FDA guidelines.
probiogen.de
ProteaImmun GmbH
ProteaImmun produces a unique range of recombinant proteases for medical and phar-
maceutical research. Our proteins are designed for structural and functional studies of
proteases screening and evaluation of protease inhibitors and modulators. Furthermore,
we develop highly sensitive ELISA Kits and antibodies.
proteaimmun.de
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Biotech Companies
PROTEKUM - Umweltinstitut GmbH, Oranien-
burg
We plan to eliminated fluid und solid waste products in a manner which is compatible
with environment protection. Our methodology is largely based on painstaking analysis.
We use modern equipment and scientific methods. Protekum offers high-quality products
and services in environmental analysis redevelopment.
protekum.de
Proteome Factory AG
Biomarker & target discovery, validation, analysis of food and ingredients, absolute
quantification of proteins and peptides, sequencing and characterization of proteins and
antibodies (CDR), 2DE and LC-MS based proteomics studies, pharmacokinetics, pharmaco,
immuno and membrane proteomics, protein identification, characterization of proteins
and peptides (PTMs, e. g. phosphorylation, glycosilation), quality control, mass determina-
tion, N-terminal amino acid sequencing, silver staining kit etc.
proteomefactory.com
Provitro GmbH
Provitro combines more than ten years of experiences in commercialisation of cell culture
technologies, Tissue Microarrays and immunohistochemical analyses with the scientific
expertise of the Pathological Institute of the Charité, Berlin. Based on a quality manage-
ment system according to ISO 9001:2008, we provide our customers not only with high-
quality products, CE marked in-vitro diagnostics and state-of-the-art services but also
with individual solutions for their specific requests.
provitro.de
Rapidozym Gesellschaft für Laborhandel und
DNA Diagnostika mbH
Expertise of cell biologists cell manufacturing and clean room technology specialists.
Focuses on clinical stem cell product development portfolio are stroke, myocardial infarc-
tion and plastic surgery.
RENESA UG (haftungsbeschränkt)
Manufacturing and distribution of rapid tests, mainly for medical purposes (Point of Care
Testing).
renesa.de
Revotar Biopharmaceuticals AG
Revotar develops innovative small molecule drugs (SMD) for the treatment of chronic
inflammatory disorders such as, chronic obstructive pulmonary disease (COPD), Acute Lung
Injury (ALI/ARDS) and ischemia/reperfusion. With its drug candidate bimosiamose, Revotar
has the worldwide most advanced pan-selectin-antagonist in clinical development in its
product pipeline.
revotar.de
RiNA GmbH
RiNA has developed systems for cell-free protein biosynthesis based on pro- and eukaryotic
cell lysates. A synthesis service is realised in RiNA's own laboratories and complements the
EasyXpress Kits (Qiagen). The purchase of Roche’s RTS-products enables RiNA now to be
a key player in the field of cellfree biosynthesis with a large variety of products. Another
research focus is the development of aptamers (DNA and RNA) for biosensors.
rina-gmbh.eu
RIPAC-LABOR GmbH
RIPAC-LABOR offers high-quality diagnoses of bacterial infections, particularly in poultry,
pigs and cattle, but also in other farm and domestic animals. The company uses pathogen
differentiation to provide quick and effective methods for fighting pathogens. It performs
resistance tests and epidemiological analyses and also focuses on producing herd-specific
vaccines.
ripac-labor.de
RNAx GmbH
RNAx specializes in RNA-Interference services. It offers functional validations of si- and
shRNAs, target validation studies using automated high throughput approaches, as well as
whole genome screens with automated assays.
RNAx.de
RNL Europe GmbH
Manufacturing of stem cells from bone marrow and adipose tissue for therapeutic and
plastic-aesthetical application. Manufacturing of adult stem cells for research (mesenchy-
mal stem cells, endothelial precursor cells). Banking of stem cells.
pharmicell.eu
Roboklon GmbH
Distribution, Marketing and Development of Products for Molecular Biological Research and
Genetic Engineering.
roboklon.de
ROVALAB GmbH
Our Master Mixes for QPCR, Standard-, Hot Start- and High Fidelity PCR as well as our high
quality critical raw materials and reagents such as DNA Polymerases and dNTPs are designed
to help you successfully and rapidly solve your scientific and manufacturing tasks.
rovalab.com
Royal Biotech GmbH
Royal focuses on developing, manufacturing and marketing innovative kits, portable or
micro-structured systems, and the next generation of diagnostic chips for near real-time
environmental, food safety, disease and laboratory diagnostics
royalbiotech.de
Scienion AG
Scienion is a life science company in the markets of dispensing systems and microar-
ray technologies. The product portfolio comprises hardware, consumables and services.
Scienion’s leading product is the sciFLEXARRAYER dispensing system, available in a product
line of six size versions. The dispenser allows the aspiration of ultra low liquid volumes
from different reservoirs and non-contact micro drop delivery in the picoliter to microliter
range onto a variety of carriers.
scienion.de
Sepiatec GmbH
Production, development and sales of automated HPLC machines for high-throughput
purification and fractioning of complex substance compounds
sepiatec.com
Seramun Diagnostica GmbH
Seramun offers peptide synthesis, purification and conjugation of proteins, production
of antibodies, customer research, In-vitro Diagnostics. We focus on the development and
production of enzyme immunoassays for diagnosis of viral and bacterial infections and
autoimmune diseases of the gastrointestinal tract, the development of multi-parameter
assays as microtitre plate assays and as membrane immunoassays, as well as development
of ready-to-use substrate solutions and for protein stabilizers.
seramun.com
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Biotech Companies
SGS INSTITUT FRESENIUS Berlin GmbH & Co. KG
Analytical laboratory services and consulting for development, production and quality
control of drugs
institut-fresenius.de
SIFIN Institut für Immunpräparate und Nähr-
medien GmbH Berlin
Development, production and purification of monoclonal antibodies for use in diagnostics.
Development and production of blood grouping reagents, Serafol
®
bedside cards and test
reagents for serotyping of Salmonellae, Shigellae, E. coli and Yersiniae. Development and
production of culture media for microbiological diagnosis.
sifin.de
Signature Diagnostics AG
Signature Diagnostics is dedicated to the discovery, validation and commercial develop-
ment of novel diagnostic products that predict outcome and drug response in patients with
colorectal cancer (CRC), non-small cell lung cancer (NSCLC) and ovarian cancer. Signature
believes that patient selection and stratification based on molecular gene signatures will
soon become an important component of routine cancer treatment.
signature-diagnostics.de
Silence Therapeutics AG
SILENCE Therapeutics AG, Berlin, is a leading RNAi therapeutics company with strong patents
issued in the US and Europe. SILENCE has developed novel, proprietary short interfering RNA
(?siRNA?) molecules and proprietary systemic delivery systems for siRNA. SILENCE has vali-
dating partnerships with AstraZeneca ($400m), Pfizer ($95m), Quark/Novartis ($80m) and
Dainippon Sumitomo (n.d.). There are 5 clinical AtuRNAi-programs of which 4 are driven by
its partners Pfizer & Quark/Novartis. SILENCE is listed through its holding company Silence
Therapeutics plc, London, at the AIM.
silence-therapeutics.com
SLM- Speziallabor für angewandte Mikrobiolo-
gie GmbH
Microbiological quality control for medical devices, pharmaceuticals, cosmetics, drinking
water, foodstuff, monitoring in clean rooms.
slm-fiedler.de
STRATEC Molecular GmbH
STRATEC Molecular GmbH is a globally active provider of innovative system solutions for
nucleic acid sample collection, stabilization, and both manual and automated purifica-
tion from any sample type. Since 1992 the company is internationally respected for its
outstanding and high performance technology platforms and offers a broad spectrum of
superior products for molecular diagnostics, drug discovery and Life Science research.
invitek.de
Strix Diagnostics GmbH
Strix Diagnostics is a medical diagnostics company specializing in customized development
of certified analytical systems for multiparameter in-vitro diagnostics.
strix-diagnostics.de
Surflay Nanotec GmbH
Surflay Nanotec GmbH, a spin-off company from Capsulution NanoScience AG, is specialized
on coating colloidal and planar materials with functional films. Key technology is the
patented LbL-Technology
®
with polymers. Applications are in the fields of separation mate-
rials, pigment encapsulation, bio-sensing and diagnostic particles. In addition to customer
tailored projects Surflay offers an unique range of products of tunable multifunctional
nano-or microparticles and dye-labeled polymers.
surflay.com
Thanares GmbH
Development, use and marketing of analytical process for diagnostic and therapeutic
purposes. Future business activities: detection process for bioactive substances in bodily
fluids, isolation, characterization and investigation of bioactive compounds from plants,
in particular insoluble proteins or low concentrations of proteins, development of low cost
genetic systems for over-expression and/or production of such proteins.
thanares.com
TheraKine BioDelivery GmbH
Development of antibody drug delivery systems and related tasks
therakine.com
TIB MOLBIOL Syntheselabor GmbH
In 1990, TIB MOLBIOL became the first German manufacturer of oligonucleotides. In
addition to designing and synthesizing primers and probes for Real-Time PCR assays, we
develop and produce LightMix
®
Kits for Roche Diagnostics LightCycler
®
Instruments, covering
applications in Clinical Chemistry, Pharmacogenetics, Pathogen Detection, as well as Cancer
Research. TIB MOLBIOL is ISO 13485 and ISO 9001 certified.
tib-molbiol.com
TransTissue Technologies GmbH
TransTissue has been a subsidiary of BioTissue Technologies, Freiburg since September
2001. With more than 15 years of experience in regenerative medicine, the scientists of
TransTissue Technologies have developed second-generation autologous tissue replace-
ments, e. g. cartilage and bone grafts. We are mainly concerned with inventions and the
development of tissue engineering products for regenerative medicine. We offer a broad
panel of services in the field of regenerative medicine.
transtissue.com
UGA Biopharma
UGA Biopharma a private Research and Development company, focuses on Research, Devel-
opment and Commercialization of Biopharmaceutical products under contract with other
Biopharmaceutical companies. UGA Biopharma conducts power of biosciences to develop
high-tech, last generation of biomedicine, diagnostic kits, molecular biology items and
also offers world class services in biotechnology area.
ugabiopharma.com
Umwelttechnik Dr. Bartetzko GmbH
Feasibility studies, development, planning, construction and operation of biotechnological
plants for groundwater, process water and waste water purification. Accredited microbio-
logical laboratory for the investigation of drinking water, groundwater, bath water, soils,
food, anti-microbial active ingredients and sterility according to Ph.Eur, approved in accor-
dance with BiostoffV and the German infection protection act (Infektionsschutzgesetz).
bartetzko.com
VasoTissue Technologies GmbH
The company is active in the field of product development for advanced medical therapies.
For its first product - the endothelialised vascular graft ("VasoGraft")- VasoTissue obtained
a manufacturing license in 2008. Currently, VasoTissue’s focus is on conducting its first
clinical trial.
vasotissue.de
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Biotech Companies
WITA GmbH
WITA is a high technology service and product company specialized for protein and
proteome analysis using high resolution NEPHGE 2-DE (up to 410 mm x 300 mm gel size,
up to 10.000 individual protein spots) and mass spectrometry. HPLC, Edman N-terminal
sequencing, synthesis of “tricky” unusual peptides
wita.de
Zellwerk GmbH
Zellwerk produces the proprietary Z
®
RP cell cultivation system, comprising rotating bed
bioreactor, GMP Breeder, Control Unit, software. Bioreactors with 50-5000 ml volume,
0,2-2 m² seeding surface, different cell carriers, can be delivered. In this culturing system
cells grow tissue-like, being embedded in self-generated extra-cellular matrix. The
technology opens unique opportunities for the GMP-compliant expansion of stem cells and
primary cells, manufacturing of cell-seeded implants as well as production of recombinant
proteins.
zellwerk.biz
Zentrum für molekulare Onkologie GmbH
Innovative methods for diagnostic and therapy of tumor diseases - Molecular genetics
(K-RAS, PCA3, Septin9, ...) - Chemoresistance assay for prediction of chemotherapy -
Pathology Development of new biomarkers and analytical services for studies
molekulare-onkologie.eu
Zytomed Systems GmbH
Zytomed Systems’ focus is the development, production and distribution of antibodies and
detection systems for immunohistochemical cancer diagnostics as well as reagents and kits
for in-situ hybridisation.
zytomed-systems.de
Are you a technology-based firm in the bio-tech branch, and are you planning to invest
in the State of Brandenburg? We can support your project with grants, loans at reduced
interest rates and risk and equity capital. Just contact us!
InvestitionsBank des Landes Brandenburg
Phone: +49 331 660-1256 · E-mail: technologie@ilb.de · www.ilb.de
Promotion and Financing for Bio-Tech Firms
150-1471_060306_AZ_Biotech 08.03.2006 13:02 Uhr Seite 1
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Life Sciences.
Living Research.
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Ready for take off 2012:
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A vibrant network
Berlin-Brandenburg is one of Europe’s leading
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Come discover this one-of-a-kind landscape for
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www.biotop.de/business
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