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10th anniversary International Multiconference «Bioinformatics of Genome Regulation and Structure\ Systems Biology»
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səhifə | 3/8 | tarix | 22.07.2018 | ölçüsü | 0,63 Mb. | | #58223 |
| Virtual biology — the foundation
Fyodor Kolpakov
Institute of Systems Biology Ltd., Novosibirsk, Russia
Design Technological Institute of Digital Techniques SB RAS Novosibirsk, Russia
14.40–15.10
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Delineating single cell life/death decisions in the CD95/FAS network
Jörn Buchbinder1, D. Pischel2, K. Sundmacher2, R.J. Flassig2, I.N. Lavrik1
1Department of Translational Inflammation Research, Otto-von-Guericke University Magdeburg, Germany; 2Max-Planck-Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany
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14:40 – 15:10
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Regulation of TREM2 expression by an inducible, NF-kB-sensitive miRNA-34a; relevance to amyloidogenesis and cognition
Zhao Y1, Bhattacharjee S1, Jones BM1, Dua P2, Hill JM 1,3, Andreeva T 4,5, Grigorenko A 4,5, Kuznetsova I 4,5, Rogaev EI 4-7, Walter J. Lukiw 1,8
1Louisiana State University Health Sciences Center, LA, USA; 2Louisiana State Technical University, LA, USA; 3Louisiana State University Health Sciences Center, LA, USA 4Vavilov Institute of General Genetics RAS, Moscow, Russia; 5ICG SB RAS, Novosibirsk, Russia; 6Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Massachusetts, USA; 7Lomonosov Moscow State University, Moscow, Russia; 8Louisiana State University Health Sciences Center, New Orleans LA, USA
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14:00−14:20
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Viruses circulating in wild bird populations of Central and North-Eastern Eurasia: evaluation of the potential hazard to human
Аlexander Shestopalov
Scientific Institute of Clinical and Experimental Medicine, Novosibirsk, Russia
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12.55-13.10
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Identification of master-regulators for programming of spermatogonal stem cells pluripotency by the use of the geneXplain/BioUml platform
Kel A.E.1,2,*, Stelmashenko D.E.2
1Institute of Chemical Biology and Fundamental Medicine, SB RAS, Novosibirsk, Russia
2BIOSOFT.RU, Ltd, Novosibirsk, Russia
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14.30–14.45
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Solutions for analysis of NGS-data
from the company Illumina
Dania Gazizova
ООО “Альбиоген” / ALBIOGEN
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14.45–15.00
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Altered catecholaminergic, serotonergic, gabaergics, and glutamatergic genes expression in the ventral tegmental area of male mice under chronic social defeat stress: RNA-SEQ data
Anna Galyamina, I.L. Kovalenko, D.A. Smagin, N.N. Kudryavtseva
ICG SB RAS, Novosibirsk, Russia
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15.10-15.25
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Advanced capabilities of visualization and analysis of cultural models
E.R. Muslikhov, L.A. Strukova
Qvadros-Bio, LLC, Moscow, Russia
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15:10 – 15:40
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The role of B cells in pathogenetisis of Alzheimer’s disease
Kim K1, Bodogai M1, Aliseychik M2, Baljinnyam T1,2, Rogaev E2,3,4 and Arya Biragyn1*.
1LMBI, National Institute on Aging, Baltimore, MD, USA.;2Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia, 3Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, MA, USA; 4Institute of Cytology and Genetics, SB RAS, Novosibirsk Russia.
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14:20−14:40
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New and emerging viral infections. Flaviviruses and Zika virus
Valery Loktev
Vector, Novosibirsk, Russia
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14:30–14:45
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SyGraph – web system for visualization of synteny alignments and comparison of assembly contigs
Mikhail Genaev1, D. A. Afonnikov1,2
1Institute of Cytology and Genetics RAS, Novosibirsk, Russia; 2NSU, Novosibirsk, Russia
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15.00–15.15
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Differential expression in Helix lucorum statocysts under microgravity conditions
Alexander Osypov1,2, P. Kolosov1, N. Aceyev1, E. Chesnokova1, M. Roshchin1, N. Bal1, P. Balaban1
1Institute of Higher Nervous Activity and Neurophysiology of RAS, Moscow, Russia; 2Institute of Cell Biophysics of RAS, Pushchino, Russia
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15.25–15.45
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Novel approach for computational design of small molecule inhibitors of protein/protein interactions in CD95/FAS pathway
Nikita Ivanisenko1,2, A.S. Ishchenko1,2 , I.N. Lavrik1,3 , V.A. Ivanisenko1
1ICG SB RAS, Novosibirsk, Russia; 2NSU, Novosibirsk, Russia
3Otto-von Guericke-University, Magdeburg, Germany
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15:40 – 16:00
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Analysis of γδT-cell repertoire in Alzheimer’sdisease patients and individuals with no memory impairment
Maria Aliseychik1, Zolotoreva O.1, Gusev F.1, Grigorenko A.1,2, Byragin A.3, Andreeva T.1, Rogaev E.1,2
1Vavilov Institute of General Genetics RAS, Moscow, Russia; 2Department of Psychiatry, Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts, 3Immunoregulation section, LMBI, National Institute on Aging, Baltimore, MD, USA.
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14:40−15:00
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Molecular mechanisms of opisthorchiasis pathogenesis: the relationships of Opisthorchis felineus with host’s DNA
Mariya Pakharukova1, G.A. Maksimova1, J.M. Correia da Costa2, N. Vale2, V.A. Mordvinov1,3
1ICG SB RAS, Novosibirsk, Russia; 2Center for the Study Animal Science, ICETA, University of Porto, Porto, Portugal
3Institute of Molecular Biology and Biophysics, Novosibirsk, Russia
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14:45–15:00
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AIMedica - intelligent system for disease diagnostics based on text-mining analysis of scientific publications and different medical data sources
Olga Saik1,2, P.S. Demenkov1,2, A.V. Starkov3,4, T.V. Ivanisenko1,2, E.V, Gaisler3,4, V.A. Ivanisenko1,2
1ICG SB RAS, Novosibirsk, Russia; 2PB-soft LLC, Novosibirsk, Russia; 3Managing company "Lomonosov Capital" LLC, Novosibirsk, Russia; 4Intelmed Ltd, Novosibirsk, Russia
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15.15–15.30
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Generalising better: applying deep-learning to integrate deleteriousness prediction scores for whole-exome SNV studies
Ilia Korvigo, A.A. Afanasyev
Moscow Institute of Physics and Technology
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15:00−15:20
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Experimental model of opisthorchiasis as a tool for biomedical researches
Damira Avgustinovich
ICG SB RAS, Novosibirsk, Russia
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15:00–15:15
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Algorithms and tools developed by novel computing systems in biology LLC
Evgeny Cheryomushkin, S. Nikitin, T. Valeev, T. Konovalova, A. Ryabova, K. Golosov, I. Mikerova, N. Gorokhov, D. Babiy
1Novel Computing Systems in Biology LLC, Novosibirsk, Russia
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15.30–15.45
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Does thyroid divergence serve as a driver of speciation in cyprinid fishes of the genus Ballerus (teleostei)?
Boris Levin1*, A.A. Bolotovskiy1, M.A. Levina1, A.V. Nedoluzhko2, K.G. Skryabin2,3,4, S.M.Rastorguev2, E.B. Prokhortchouk3,4
1Institute of Biology of Inland Waters RAS, Borok, Russia; 2National Research Center Kurchatov Institute, Moscow, Russia; 3Institute of Bioengineering, Federal Research Center “Fundamentals of Biotechnology” RAS, Moscow, Russia; 4Lomonosov Moscow State University, Faculty of Biology, Moscow, Russia
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15.45–16.05
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Associative networks of glaucoma and apoptosis
Olga Saik1, P.S. Demenkov1, O.S. Konovalova2, M.N. Ponomareva2, N.A. Konovalova2, N.A. Kolchanov1, I.N. Lavrik3, V.A. Ivanisenko1.
1ICG SB RAS, Novosibirsk, Russia
2Tyumen State Medical Academy, Ministry of Health of the Russian Federation, Tyumen, Russia; 3Otto von Guericke University Magdeburg, Magdeburg, Germany
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15:20−15:40
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Founder effect in Siberian indigenous populations through the prism of hereditary deafness
Olga Posukh1,2, M.S. Bady-Khoo3, M.V. Zytsar1,2, V.Y. Mikhalskaia1,2, N.A.Barashkov 4,5, I.V. Morozov2,6, A.A. Bondar6
1ICG SB RAS, Novosibirsk, Russia; 2NSU, Novosibirsk, Russia; 3Perinatal Center of the Tuva Republic, Kyzyl, Russia; 4Yakut Scientific Centre of Complex Medical Problems, Yakutsk, Russia; 5M.K. Ammosov North-Eastern Federal University, Yakutsk, Russia; 6ICBFM SB RAS, Novosibirsk, Russia
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15:15–15:30
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Rule-based modeling in biouml
Nikita Mandrik1-3, E.O. Kutumova1,2, F.A. Kolpakov1,2
1Design Technological Institute of Digital Techniques SB RAS, Novosibirsk, Russia; 2Institute of Systems Biology, Novosibirsk, Russia
3Sobolev Institute of Mathematics SB RAS, Novosibirsk, Russia
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15.45–16.00
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Parameter fitting infrastructure for rule-based modelling
O.S. Sorokina1, Anatoly Sorokin2,3
1Edinburgh University, Edinburgh, UK; 2Institute of Cell Biophysics RAS, Pushchino, Russia; 3Moscow Institute of Physics and Technology, Dolgoprudny, Russia
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15:40−15:50
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Discussion
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15:30–15:45
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Improved SBGN (ML) support IN BioUML
Ilya Kiselev1, S. D. Kinsht3, F.A. Kolpakov1,2
1Design Technological Institute of Digital Techniques SB RAS, Novosibirsk, Russia
2Institute of Systems Biology, Ltd, Novosibirsk, Russia
3NSU, Novosibirsk, Russia
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Coffee break: 16.00–16.15
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16.15–16.30
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Optimization of the piggyBac transposon system for cultured Drosophila cells
Lyubov Yarinich1,2*, M.O. Lebedev1,2, A.V. Pindyurin1,2
1Institute of Molecular and Cellular Biology SB RAS, Novosibirsk, Russia; 2NSU, Novosibirsk, Russia
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16:20 – 16:50
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Experimental models for neurodegenerative pathologies studies and neuron-computer interface establishment
Sergey Kiselev
Vavilov Institute of General Genetics RAS, Moscow
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16:10−18:00
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Personalized Medicine: New Biomarkers and Molecular Targets
Chairs: Vyacheslav Lyakhovich, Sergey Sennikov
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16:10–18:20
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Poster Session
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16.30–16.45
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Using the techniques of stochastic modelling and inhomogeneous sequential pattern recognition procedure for the prediction of the development of polygenic diseases
V.F. Prokof'ev, A.V. Shevchenko, Maksim Korolev, V.I. Konenkov
Scientific Institute of clinical and experimental lymрhology SB RAS, Novosibirsk, Russia
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16:50 – 17:10
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Epigenome landscape analysis of brain cells identifies putative novel genes active in cortical neuron
Fedor Gusev1-3, Reshetov D2,3, Mitchell A4, Andreeva T2,3, Dincer A4, Solovyev V5, Grigorenko A1-3, Akbarian S 1,4 and Rogaev E1-3.
1Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, MA, USA 2 Vavilov Institute of General Genetics RAS, Moscow, Russia 3ICG SB RAS, Novosibirsk, Russia 4Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 5Softberry Inc., Mount Kisco, NY, USA
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16:10-16:25
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From pharmacogenetics to modern pharmacotherapy
Valentin Vavilin, Vyacheslav Lyakhovich
Institute of Molecular Biology and Biophysics, Novosibirsk, Russia
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16.45–17.00
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The bioinfornational comparison of CRISPR/Cas system structure of Yyersinia pseudotuberculosis strains isolated from different regions
Nadezhda Peretolchina1, Y.P. Dzhioev1,2, A.Y. Borisenko1, E.A. Voskresenskaya3, A.I. Paramonov2, L.A. Stepanenko1, V.I. Zlobin1
1Irkutsk State Medical University, Irkutsk, Russia
2Scientific Center of family health problems and human reproduction, Irkutsk, Russia
3Institut Pasteur, Saint Petersburg, Russia
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17:10 – 17:30
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Aging and longevity from genomic perspectives
Andreeva T.V., Gusev F.E., Reshetov D.A., Shagam L.I., Kunizheva S.S., Yigit S., Geyko A.V., Andrey Manachov ., Kuznetsova I., Aliseychik M., Lisenkova A., Lukyanov E., Protasova M., Buzina A.N., Lukiw W.J.d, Byragin A., Grigorenko A. and Rogaev E.I.
1Institute of General Genetics RAS, Moscow, Russia; 2ICG SB RAS, Novosibirsk, Russia; 3Gaziosmanpasa University Medical School, Tokat, Turkiye; 4Louisiana State University Health Sciences Center, New Orleans LA USA; Departments of Neurology and Ophthalmology, Louisiana State University Health Sciences Center, New Orleans LA 70112 USA; eLMBI, National Institute on Aging, Baltimore, MD, USA; fBrudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, MA, USA
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16:25−16:40
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Modern biomarkers of coronary atherosclerosis and its complications
Juliya Ragino, E.V. Kashtanova, Ya.V. Polonskaya
Institute of Internal and Preventive Medicine, Novosibirsk, Russia
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17.00–17.15
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Theoretical model of mitotic spindle microtubule growth for FRAP curve interpretation
Leonid Omelyanchuk1,2, A.F. Munzarova1,2, T.Y. Mikhailova2
1Institute of Molecular and Cellular Biology, Novosibirsk, Russia
2NSU, Novosibirsk, Russia
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16:40−16:55
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Inverse changes in serum concentrations of inflammatory and angiogenic growth factors in patients with type 2 diabetes
Vadim Klimontov, D.M. Bulumbaeva, N.V. Tyan, N.B. Orlov, A.P. Lykov, V.I. Konenkov SICEL, Novosibirsk, Russia
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17.15–17.30
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Assessment of translation efficency from ribosome profiling and mRNA-seq data
I.S. Yevshin1,2, R.N. Sharipov1,2, Oksana Volkova3
1Design Technological Institute of Digital Techniques, SB RAS, Novosibirsk, Russia; 2Institute of Systems Biology, Ltd, Novosibirsk, Russia; 3 The Federal Research Center ICG SB RAS, Novosibirsk, Russia
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17:30 – 17: 50
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Reconstruction of molecular-genetic networks common for
Alzheimer's disease
Olga Saik1, Rogaev EI 1-3
1 ICG SB RAS, 630090 Novosibirsk, Russia; 2Vavilov Institute of General Genetics RAS, Moscow, Russia; 3Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Massachusetts, USA
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16:55−17:10
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Serological markers in rheumatoid arthritis: circulating DNA and autoreactive antibodies
Elena Rykova1,2, A. Sizikov3, D. Roggenbuck4,O. Antonenko5, L. Bryzgalov6, E. Morozkin1,7, V. Vlasov1, P. Laktionov1,7, V. Kozlov3
1ICBFM SB RAS, Novosibirsk, Russia; 2Novosibirsk State Technical University, Novosibirsk, Russia
3Research Institute of Fundamental and Clinical Immunology, Novosibirsk, Russia 4Brandenburg Technical University, Berlin, Germany; 5Institute of Molecular and Cellular Biology SB RAS; 6ICG SB RAS; 7Academician E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Novosibirsk, Russia
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17.30–17.45
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Principal organization of physiological regulator
Vyacheslav Fedorov
Institute of Laser Physics SB RAS, Novosibirsk, Russia
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17:50 – 18:20
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Discussion
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17.45–18.00
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