Louis Pasteur & Germ Theory Beliefs about disease in19th Century



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Louis Pasteur & Germ Theory


Beliefs about disease in19th Century

  • People knew there was a link between dirt and disease, but could not explain the link.

  • People explained disease as seeds bad seeds in the air known as miasma.

  • 1850s &1860s breakthrough in the cause of disease.



Step 1: Discovery of Micro-organisms

  • Anthony Van Leeuwenhoek made one of the earliest microscopes.

  • Discovered micro-organisms which he called animalcules.

  • Microscopes not as good as today.



Step 2: Improved microscopes

  • 1800s purer glass produced = better lenses for microscope.

  • 1830 Joseph Lister develops a microscope which can magnify x1000



Step 3: Louis Pasteur’s germ theory

  • Old Theory: spontaneous generation

    • micro-organisms are the result of decaying matter.
  • New Theory: germ theory

    • micro-organisms cause decaying matter.
    • Pasteur showed you could kill the micro-organisms by applying heat - PASTEURISATION.


Step 4: Germ theory vs spontaneous generation

  • Pasteur now had to prove his theory.

  • In competition with French scientist Pouchet.

  • Conducted an experiment showing that microbes in the air caused decay.

  • 1861 published his ‘germ theory’



Step 5: Linking micro-organisms to disease

  • Pasteur showed micro-organisms made wine and beer go bad.

  • Could germs cause disease?

  • Another experiment!

    • Proved that a micro-organism was causing disease in silk worms.


Step 6: Proving the link between bacteria and human disease.



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